Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment
Abstract Pharmacist’s geriatric assessment can provide valuable insights into potential deprescribing targets, while including important information on various health-related domains. Data collected from a geriatric assessment questionnaire, for 388 patients, from the Croatian cohort of the EuroAgei...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-03-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-024-56780-1 |
| _version_ | 1797259330452455424 |
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| author | Iva Bužančić Margita Držaić Ingrid Kummer Maja Ortner Hadžiabdić Jovana Brkić Daniela Fialová |
| author_facet | Iva Bužančić Margita Držaić Ingrid Kummer Maja Ortner Hadžiabdić Jovana Brkić Daniela Fialová |
| author_sort | Iva Bužančić |
| collection | DOAJ |
| description | Abstract Pharmacist’s geriatric assessment can provide valuable insights into potential deprescribing targets, while including important information on various health-related domains. Data collected from a geriatric assessment questionnaire, for 388 patients, from the Croatian cohort of the EuroAgeism H2020 ESR 7 international project, along with guideline-based deprescribing criteria, were used to analyse potentially inappropriate prescribing of four medication groups (benzodiazepines (BZN), proton pump inhibitors (PPI), opioids, and non-steroidal anti-inflammatory drugs (NSAID)), and to assess the deprescribing potential. Binary logistic regression was used to explore the effects of age, gender, number of medicines and diagnoses, self-reported health, frailty score, and healthcare utilization on the likelihood of needing deprescribing. More than half of participants (n = 216, 55.2%) are candidates for deprescribing, with 31.1% of PPI, 74.8% of NSAID, 75% of opioid, and 96.1% of BZN users meeting at least one criterion. Most common criteria for deprescribing were inappropriately long use and safety concerns. Women (aOR = 2.58; p < 0.001), those reporting poor self-reported health (aOR = 5.14; p < 0.001), and those exposed to polypharmacy (aOR = 1.29; p < 0.001) had higher odds of needing to have medicines deprescribed. The high rate of deprescribing potential warrants prompt action to increase patient safety and decrease polypharmacy. Pharmacist’s geriatric assessment and deprescribing-focused medication review could be used to lead a personalised approach. |
| first_indexed | 2024-04-24T23:07:43Z |
| format | Article |
| id | doaj.art-150c676ffcc842df94455bd13dad4a19 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-24T23:07:43Z |
| publishDate | 2024-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-150c676ffcc842df94455bd13dad4a192024-03-17T12:22:02ZengNature PortfolioScientific Reports2045-23222024-03-0114111010.1038/s41598-024-56780-1Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessmentIva Bužančić0Margita Držaić1Ingrid Kummer2Maja Ortner Hadžiabdić3Jovana Brkić4Daniela Fialová5City Pharmacies ZagrebCity Pharmacies ZagrebDepartment of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles UniversityFaculty of Pharmacy and Biochemistry, Center for Applied Pharmacy, University of ZagrebDepartment of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles UniversityDepartment of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles UniversityAbstract Pharmacist’s geriatric assessment can provide valuable insights into potential deprescribing targets, while including important information on various health-related domains. Data collected from a geriatric assessment questionnaire, for 388 patients, from the Croatian cohort of the EuroAgeism H2020 ESR 7 international project, along with guideline-based deprescribing criteria, were used to analyse potentially inappropriate prescribing of four medication groups (benzodiazepines (BZN), proton pump inhibitors (PPI), opioids, and non-steroidal anti-inflammatory drugs (NSAID)), and to assess the deprescribing potential. Binary logistic regression was used to explore the effects of age, gender, number of medicines and diagnoses, self-reported health, frailty score, and healthcare utilization on the likelihood of needing deprescribing. More than half of participants (n = 216, 55.2%) are candidates for deprescribing, with 31.1% of PPI, 74.8% of NSAID, 75% of opioid, and 96.1% of BZN users meeting at least one criterion. Most common criteria for deprescribing were inappropriately long use and safety concerns. Women (aOR = 2.58; p < 0.001), those reporting poor self-reported health (aOR = 5.14; p < 0.001), and those exposed to polypharmacy (aOR = 1.29; p < 0.001) had higher odds of needing to have medicines deprescribed. The high rate of deprescribing potential warrants prompt action to increase patient safety and decrease polypharmacy. Pharmacist’s geriatric assessment and deprescribing-focused medication review could be used to lead a personalised approach.https://doi.org/10.1038/s41598-024-56780-1DeprescribingHealthy ageingGeriatricsGeriatric assessmentPolypharmacy |
| spellingShingle | Iva Bužančić Margita Držaić Ingrid Kummer Maja Ortner Hadžiabdić Jovana Brkić Daniela Fialová Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment Scientific Reports Deprescribing Healthy ageing Geriatrics Geriatric assessment Polypharmacy |
| title | Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment |
| title_full | Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment |
| title_fullStr | Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment |
| title_full_unstemmed | Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment |
| title_short | Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment |
| title_sort | deprescribing potential of commonly used medications among community dwelling older adults insights from a pharmacist s geriatric assessment |
| topic | Deprescribing Healthy ageing Geriatrics Geriatric assessment Polypharmacy |
| url | https://doi.org/10.1038/s41598-024-56780-1 |
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