An experimental-mathematical approach to predict tumor cell growth as a function of glucose availability in breast cancer cell lines.
We present the development and validation of a mathematical model that predicts how glucose dynamics influence metabolism and therefore tumor cell growth. Glucose, the starting material for glycolysis, has a fundamental influence on tumor cell growth. We employed time-resolved microscopy to track th...
Main Authors: | Jianchen Yang, Jack Virostko, David A Hormuth, Junyan Liu, Amy Brock, Jeanne Kowalski, Thomas E Yankeelov |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0240765 |
Similar Items
-
Comparing mechanism-based and machine learning models for predicting the effects of glucose accessibility on tumor cell proliferation
by: Jianchen Yang, et al.
Published: (2023-06-01) -
A data assimilation framework to predict the response of glioma cells to radiation
by: Junyan Liu, et al.
Published: (2023-01-01) -
Mathematical characterization of population dynamics in breast cancer cells treated with doxorubicin
by: Emily Y. Yang, et al.
Published: (2022-09-01) -
A mathematical model for predicting the spatiotemporal response of breast cancer cells treated with doxorubicin
by: Hugo J. M. Miniere, et al.
Published: (2024-12-01) -
A Multi-Compartment Model of Glioma Response to Fractionated Radiation Therapy Parameterized via Time-Resolved Microscopy Data
by: Junyan Liu, et al.
Published: (2022-02-01)