Autophagy in Osteosarcoma Cancer Stem Cells Is Critical Process which Can Be Targeted by the Antipsychotic Drug Thioridazine

Autophagy in Osteosarcoma Cancer Stem Cells Is Critical Process which Can Be Targeted by the Antipsychotic Drug Thioridazine

Cancer stem cells (CSCs) represent a minor population of cancer cells with stem cell-like properties which are able to fuel tumor growth and resist conventional treatments. Autophagy has been described to be upregulated in some CSCs and to play a crucial role by maintaining stem features and promoti...

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Bibliographic Details
Main Authors: Olivier Camuzard, Marie-Charlotte Trojani, Sabine Santucci-Darmanin, Sophie Pagnotta, Véronique Breuil, Georges F. Carle, Valérie Pierrefite-Carle
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
autophagy
osteosarcoma
cancer stem cells
Na+/K+ ATPase
autosis
Online Access:https://www.mdpi.com/2072-6694/12/12/3675

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