A novel recombinant serotype 4 fowl adenovirus expressing fiber-2 protein of duck adenovirus 3

A novel recombinant serotype 4 fowl adenovirus expressing fiber-2 protein of duck adenovirus 3

Recently, the highly pathogenic serotype 4 fowl adenovirus (FAdV-4) and duck adenovirus 3 (DAdV-3) were outbroken and widespread, causing substantial economic losses to the duck industry. Therefore, there is an urgent need to generate a recombinant genetic engineering vaccine candidate against both...

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Bibliographic Details
Main Authors: Yiwen Guo, Yun Lin, Quan Xie, Wenyuan Zhang, Zhenqi Xu, Yifei Chao, Xudong Cao, Huiru Jiang, Han Li, Tuofan Li, Zhimin Wan, Hongxia Shao, Aijian Qin, Jianqiang Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
DAdV-3
fiber-2
recombinant FAdV-4
CRISPR/Cas9
expression
replication
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1177866/full

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