Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membrane
GABAB receptors mediate the effects of the main inhibitory neurotransmitter in the brain. Here, authors identify the cytoskeletal protein filamin A as a key player that controls the exact location and function of GABAB receptors at the cell surface.
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-35708-1 |
| _version_ | 1797958537138143232 |
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| author | Marie-Lise Jobin Sana Siddig Zsombor Koszegi Yann Lanoiselée Vladimir Khayenko Titiwat Sungkaworn Christian Werner Kerstin Seier Christin Misigaiski Giovanna Mantovani Markus Sauer Hans M. Maric Davide Calebiro |
| author_facet | Marie-Lise Jobin Sana Siddig Zsombor Koszegi Yann Lanoiselée Vladimir Khayenko Titiwat Sungkaworn Christian Werner Kerstin Seier Christin Misigaiski Giovanna Mantovani Markus Sauer Hans M. Maric Davide Calebiro |
| author_sort | Marie-Lise Jobin |
| collection | DOAJ |
| description | GABAB receptors mediate the effects of the main inhibitory neurotransmitter in the brain. Here, authors identify the cytoskeletal protein filamin A as a key player that controls the exact location and function of GABAB receptors at the cell surface. |
| first_indexed | 2024-04-11T00:21:30Z |
| format | Article |
| id | doaj.art-151c7286e0224e3e936b73cfadb10add |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T00:21:30Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-151c7286e0224e3e936b73cfadb10add2023-01-08T12:15:47ZengNature PortfolioNature Communications2041-17232023-01-0114111410.1038/s41467-022-35708-1Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membraneMarie-Lise Jobin0Sana Siddig1Zsombor Koszegi2Yann Lanoiselée3Vladimir Khayenko4Titiwat Sungkaworn5Christian Werner6Kerstin Seier7Christin Misigaiski8Giovanna Mantovani9Markus Sauer10Hans M. Maric11Davide Calebiro12Institute for Pharmacology and Toxicology, University of WürzburgInstitute for Pharmacology and Toxicology, University of WürzburgInstitute of Metabolism and Systems Research, University of BirminghamInstitute of Metabolism and Systems Research, University of BirminghamRudolf Virchow Center, Center for Integrative and Translational Bioimaging, University of WürzburgInstitute for Pharmacology and Toxicology, University of WürzburgDepartment of Biotechnology and Biophysics, Biocenter, University of WürzburgInstitute for Pharmacology and Toxicology, University of WürzburgInstitute for Pharmacology and Toxicology, University of WürzburgEndocrinology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore PoliclinicoDepartment of Biotechnology and Biophysics, Biocenter, University of WürzburgRudolf Virchow Center, Center for Integrative and Translational Bioimaging, University of WürzburgInstitute for Pharmacology and Toxicology, University of WürzburgGABAB receptors mediate the effects of the main inhibitory neurotransmitter in the brain. Here, authors identify the cytoskeletal protein filamin A as a key player that controls the exact location and function of GABAB receptors at the cell surface.https://doi.org/10.1038/s41467-022-35708-1 |
| spellingShingle | Marie-Lise Jobin Sana Siddig Zsombor Koszegi Yann Lanoiselée Vladimir Khayenko Titiwat Sungkaworn Christian Werner Kerstin Seier Christin Misigaiski Giovanna Mantovani Markus Sauer Hans M. Maric Davide Calebiro Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membrane Nature Communications |
| title | Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membrane |
| title_full | Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membrane |
| title_fullStr | Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membrane |
| title_full_unstemmed | Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membrane |
| title_short | Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membrane |
| title_sort | filamin a organizes γ aminobutyric acid type b receptors at the plasma membrane |
| url | https://doi.org/10.1038/s41467-022-35708-1 |
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