A Synthetic Peptide, CK2.3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway

A Synthetic Peptide, CK2.3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway

The skeletal system plays an important role in the development and maturation process. Through the bone remodeling process, 10% of the skeletal system is renewed every year. Osteoblasts and osteoclasts are two major bone cells that are involved in the development of the skeletal system, and their ac...

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Bibliographic Details
Main Authors: John Nguyen, Semaj Kelly, Ryan Wood, Brian Heubel, Anja Nohe
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Journal of Developmental Biology
Subjects:
osteoporosis
casein kinase 2
BMP2
CK2.3
osteoclastogenesis
BMPRIa
Online Access:https://www.mdpi.com/2221-3759/8/3/12

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