Zinc oxide eugenol paste as a dressing material on surgical raw wounds after wide excision of oral potentially malignant disorders: A prospective controlled clinical trial

Introduction: Oral potentially malignant disorders (PMDs) have a high risk to develop oral squamous cell carcinomas which are responsible for approximately 270,000 patients annually worldwide. When surgical excision of PMD is done, a raw denuded area is formed, which is required to be addressed. The...

Full description

Bibliographic Details
Main Authors: Vishal, Tanya Khaitan, V K Prajapati
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Indian Journal of Dental Sciences
Subjects:
Online Access:http://www.ijds.in/article.asp?issn=0976-4003;year=2021;volume=13;issue=2;spage=98;epage=102;aulast=Khaitan
_version_ 1818933706075668480
author Vishal
Tanya Khaitan
V K Prajapati
author_facet Vishal
Tanya Khaitan
V K Prajapati
author_sort Vishal
collection DOAJ
description Introduction: Oral potentially malignant disorders (PMDs) have a high risk to develop oral squamous cell carcinomas which are responsible for approximately 270,000 patients annually worldwide. When surgical excision of PMD is done, a raw denuded area is formed, which is required to be addressed. The present study was done to determine the effectiveness of zinc oxide (ZnO) eugenol paste as a dressing material of such surgical raw wounds and to assess its usefulness. Materials and Methods: A total of thirty patients with oral PMDs underwent wide surgical excision under local anesthesia. ZnO eugenol paste with preformed sterile gauge piece was applied in denuded area as dressing and sutured. Intraoperative evaluation was done on the following criteria: handling of ZnO eugenol paste and hemostasis achieved; postoperative evaluation included pain, adherence, granulation, epithelialization, reactivity to the ZnO eugenol. and overall usefulness as an intraoral dressing material. Results: Good hemostasis was obtained in 24 cases (80%). The mean score of pain was recorded as 3.5. Twenty-three cases (76%) showed granulation and epithelialization was rated as good. ZnO eugenol paste with the help of sutures showed good adherence in 29 cases (96.6%). No allergic reaction was noted. ZnO eugenol dressing was proved to be very effective in 28 cases (93.3%), effective in 2 cases (6.7%), and ineffective in 0 cases (0%). Conclusion: The chemical, physiological, and biological properties of ZnO eugenol have proved to be useful as a dressing material in cases of raw wound formed after excision of oral PMDs It is not a replacement for skin graft or collagen biodegradable membrane, but it can be one of the armamentaria for the oral surgeon in such cases.
first_indexed 2024-12-20T04:52:38Z
format Article
id doaj.art-15218beb909e4392bb147854c39d1096
institution Directory Open Access Journal
issn 0976-4003
2231-2293
language English
last_indexed 2024-12-20T04:52:38Z
publishDate 2021-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Dental Sciences
spelling doaj.art-15218beb909e4392bb147854c39d10962022-12-21T19:52:48ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Sciences0976-40032231-22932021-01-011329810210.4103/IJDS.IJDS_170_20Zinc oxide eugenol paste as a dressing material on surgical raw wounds after wide excision of oral potentially malignant disorders: A prospective controlled clinical trialVishalTanya KhaitanV K PrajapatiIntroduction: Oral potentially malignant disorders (PMDs) have a high risk to develop oral squamous cell carcinomas which are responsible for approximately 270,000 patients annually worldwide. When surgical excision of PMD is done, a raw denuded area is formed, which is required to be addressed. The present study was done to determine the effectiveness of zinc oxide (ZnO) eugenol paste as a dressing material of such surgical raw wounds and to assess its usefulness. Materials and Methods: A total of thirty patients with oral PMDs underwent wide surgical excision under local anesthesia. ZnO eugenol paste with preformed sterile gauge piece was applied in denuded area as dressing and sutured. Intraoperative evaluation was done on the following criteria: handling of ZnO eugenol paste and hemostasis achieved; postoperative evaluation included pain, adherence, granulation, epithelialization, reactivity to the ZnO eugenol. and overall usefulness as an intraoral dressing material. Results: Good hemostasis was obtained in 24 cases (80%). The mean score of pain was recorded as 3.5. Twenty-three cases (76%) showed granulation and epithelialization was rated as good. ZnO eugenol paste with the help of sutures showed good adherence in 29 cases (96.6%). No allergic reaction was noted. ZnO eugenol dressing was proved to be very effective in 28 cases (93.3%), effective in 2 cases (6.7%), and ineffective in 0 cases (0%). Conclusion: The chemical, physiological, and biological properties of ZnO eugenol have proved to be useful as a dressing material in cases of raw wound formed after excision of oral PMDs It is not a replacement for skin graft or collagen biodegradable membrane, but it can be one of the armamentaria for the oral surgeon in such cases.http://www.ijds.in/article.asp?issn=0976-4003;year=2021;volume=13;issue=2;spage=98;epage=102;aulast=Khaitandressingexcisionleukoplakiazinc oxide eugenol
spellingShingle Vishal
Tanya Khaitan
V K Prajapati
Zinc oxide eugenol paste as a dressing material on surgical raw wounds after wide excision of oral potentially malignant disorders: A prospective controlled clinical trial
Indian Journal of Dental Sciences
dressing
excision
leukoplakia
zinc oxide eugenol
title Zinc oxide eugenol paste as a dressing material on surgical raw wounds after wide excision of oral potentially malignant disorders: A prospective controlled clinical trial
title_full Zinc oxide eugenol paste as a dressing material on surgical raw wounds after wide excision of oral potentially malignant disorders: A prospective controlled clinical trial
title_fullStr Zinc oxide eugenol paste as a dressing material on surgical raw wounds after wide excision of oral potentially malignant disorders: A prospective controlled clinical trial
title_full_unstemmed Zinc oxide eugenol paste as a dressing material on surgical raw wounds after wide excision of oral potentially malignant disorders: A prospective controlled clinical trial
title_short Zinc oxide eugenol paste as a dressing material on surgical raw wounds after wide excision of oral potentially malignant disorders: A prospective controlled clinical trial
title_sort zinc oxide eugenol paste as a dressing material on surgical raw wounds after wide excision of oral potentially malignant disorders a prospective controlled clinical trial
topic dressing
excision
leukoplakia
zinc oxide eugenol
url http://www.ijds.in/article.asp?issn=0976-4003;year=2021;volume=13;issue=2;spage=98;epage=102;aulast=Khaitan
work_keys_str_mv AT vishal zincoxideeugenolpasteasadressingmaterialonsurgicalrawwoundsafterwideexcisionoforalpotentiallymalignantdisordersaprospectivecontrolledclinicaltrial
AT tanyakhaitan zincoxideeugenolpasteasadressingmaterialonsurgicalrawwoundsafterwideexcisionoforalpotentiallymalignantdisordersaprospectivecontrolledclinicaltrial
AT vkprajapati zincoxideeugenolpasteasadressingmaterialonsurgicalrawwoundsafterwideexcisionoforalpotentiallymalignantdisordersaprospectivecontrolledclinicaltrial