Development and Characterization of Sustained-Released Donepezil Hydrochloride Solid Dispersions Using Hot Melt Extrusion Technology
The aim of this work was to develop the sustained release formulation of donepezil hydrochloride (DH) using the hot-melt extruded solid dispersion technique via the rational screening of hydrophobic carriers. Hydrophobic carriers with different physicochemical properties such as pH-independent swell...
Main Authors: | Abdullah Alshetaili, Bjad K. Almutairy, Sultan M. Alshehri, Michael A. Repka |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/13/2/213 |
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