QTc interval is associated with increased inflammatory markers (neutrophil-to-lymphocyte ratio and LDH level) in COVID-19 patients
Purpose: This study aimed to investigate the association between QTc interval and laboratory parameters in COVID-19 patients before and after the treatment. Materials and Methods: Forty-three COVID-19 patients who had baseline and follow-up ECG findings and laboratory reports were evaluated and 40 p...
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| Format: | Article |
| Language: | English |
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Cukurova University
2021-12-01
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| Series: | Cukurova Medical Journal |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/1953100 |
| _version_ | 1797915562760732672 |
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| author | Şerife Torun Irem Karaman Nurtaç Özer Çaşıt Olgun Çelik M. Şule Akçay |
| author_facet | Şerife Torun Irem Karaman Nurtaç Özer Çaşıt Olgun Çelik M. Şule Akçay |
| author_sort | Şerife Torun |
| collection | DOAJ |
| description | Purpose: This study aimed to investigate the association between QTc interval and laboratory parameters in COVID-19 patients before and after the treatment.
Materials and Methods: Forty-three COVID-19 patients who had baseline and follow-up ECG findings and laboratory reports were evaluated and 40 patients were included in the study.
Results: Among 40 patients, 16 were women and 24 were men. The neutrophil-to-lymphocyte ratio (NLR) and corrected QT (QTc) interval were significantly higher in females than males. After the treatment, a significant fall in CRP and ferritin values, and significantly prolonged QTc interval were seen. A significant positive correlation was observed between QTc interval and age, LDH levels, neutrophil and leukocyte count, NLR, magnesium levels, and heart rate of the patients prior to treatment. A positive correlation was observed between increased QTc interval and decreased LDH levels and NLR after treatment.
Conclusion: QTc prolongation was associated with increased inflammatory markers, increased NLR and LDH levels before and after treatment in COVID-19 patients. The increase in the QTc interval was correlated with the reduction in LDH levels and NLR with treatment. |
| first_indexed | 2024-04-10T12:43:40Z |
| format | Article |
| id | doaj.art-1523fb504bd2488489c76fed5fde0894 |
| institution | Directory Open Access Journal |
| issn | 2602-3040 |
| language | English |
| last_indexed | 2024-04-10T12:43:40Z |
| publishDate | 2021-12-01 |
| publisher | Cukurova University |
| record_format | Article |
| series | Cukurova Medical Journal |
| spelling | doaj.art-1523fb504bd2488489c76fed5fde08942023-02-15T16:14:10ZengCukurova UniversityCukurova Medical Journal2602-30402021-12-014641711171848QTc interval is associated with increased inflammatory markers (neutrophil-to-lymphocyte ratio and LDH level) in COVID-19 patientsŞerife Torun0Irem Karaman1Nurtaç Özer2Çaşıt Olgun Çelik3M. Şule Akçay4Başkent Üniversitesi tıp fakültesi Konya Uygulama ve Araştırma merkeziBAHÇEŞEHİR ÜNİVERSİTESİ, TIP FAKÜLTESİBAŞKENT ÜNİVERSİTESİ, KONYA UYGULAMA ARAŞTIRMA VE UYGULAMA MERKEZİBAŞKENT ÜNİVERSİTESİ, KONYA UYGULAMA ARAŞTIRMA VE UYGULAMA MERKEZİBAŞKENT ÜNİVERSİTESİ, TIP FAKÜLTESİPurpose: This study aimed to investigate the association between QTc interval and laboratory parameters in COVID-19 patients before and after the treatment. Materials and Methods: Forty-three COVID-19 patients who had baseline and follow-up ECG findings and laboratory reports were evaluated and 40 patients were included in the study. Results: Among 40 patients, 16 were women and 24 were men. The neutrophil-to-lymphocyte ratio (NLR) and corrected QT (QTc) interval were significantly higher in females than males. After the treatment, a significant fall in CRP and ferritin values, and significantly prolonged QTc interval were seen. A significant positive correlation was observed between QTc interval and age, LDH levels, neutrophil and leukocyte count, NLR, magnesium levels, and heart rate of the patients prior to treatment. A positive correlation was observed between increased QTc interval and decreased LDH levels and NLR after treatment. Conclusion: QTc prolongation was associated with increased inflammatory markers, increased NLR and LDH levels before and after treatment in COVID-19 patients. The increase in the QTc interval was correlated with the reduction in LDH levels and NLR with treatment.https://dergipark.org.tr/tr/download/article-file/1953100covid-19elektrokardiyogramqtc aralığıinflamasyonnötrofil-lenfosit oranıldhcovid-19electrocardiogramqtc intervalinflammationneutrophil-to-lymphocyte ratioldh |
| spellingShingle | Şerife Torun Irem Karaman Nurtaç Özer Çaşıt Olgun Çelik M. Şule Akçay QTc interval is associated with increased inflammatory markers (neutrophil-to-lymphocyte ratio and LDH level) in COVID-19 patients Cukurova Medical Journal covid-19 elektrokardiyogram qtc aralığı inflamasyon nötrofil-lenfosit oranı ldh covid-19 electrocardiogram qtc interval inflammation neutrophil-to-lymphocyte ratio ldh |
| title | QTc interval is associated with increased inflammatory markers (neutrophil-to-lymphocyte ratio and LDH level) in COVID-19 patients |
| title_full | QTc interval is associated with increased inflammatory markers (neutrophil-to-lymphocyte ratio and LDH level) in COVID-19 patients |
| title_fullStr | QTc interval is associated with increased inflammatory markers (neutrophil-to-lymphocyte ratio and LDH level) in COVID-19 patients |
| title_full_unstemmed | QTc interval is associated with increased inflammatory markers (neutrophil-to-lymphocyte ratio and LDH level) in COVID-19 patients |
| title_short | QTc interval is associated with increased inflammatory markers (neutrophil-to-lymphocyte ratio and LDH level) in COVID-19 patients |
| title_sort | qtc interval is associated with increased inflammatory markers neutrophil to lymphocyte ratio and ldh level in covid 19 patients |
| topic | covid-19 elektrokardiyogram qtc aralığı inflamasyon nötrofil-lenfosit oranı ldh covid-19 electrocardiogram qtc interval inflammation neutrophil-to-lymphocyte ratio ldh |
| url | https://dergipark.org.tr/tr/download/article-file/1953100 |
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