Etoposide-induced DNA damage in a chromosomal breakpoint of RUNX1 gene is independent of RUNX1 expression
In this work, we analyzed the association between RUNX1 gene expression and the accessibility of BCR3, one of RUNX1 gene breakpoint regions involved in the chromosomal translocation (8;21), a frequent translocation in treatment-related acute myeloid leukemia patients. To this end, we evaluate DNA da...
Main Authors: | Nicolás Schnake, Soraya Gutiérrez |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | Leukemia Research Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213048919300457 |
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