Radiotherapeutic alternatives for previously irradiated recurrent gliomas

<p>Abstract</p> <p>Re-irradiation for recurrent gliomas has been discussed controversially in the past. This was mainly due to only marginal palliation while being associated with a high risk for side effects using conventional radiotherapy.</p> <p>With modern high-prec...

Full description

Bibliographic Details
Main Authors: Schulz-Ertner Daniela, Debus Jürgen, Combs Stephanie E
Format: Article
Language:English
Published: BMC 2007-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/167
_version_ 1819088565120794624
author Schulz-Ertner Daniela
Debus Jürgen
Combs Stephanie E
author_facet Schulz-Ertner Daniela
Debus Jürgen
Combs Stephanie E
author_sort Schulz-Ertner Daniela
collection DOAJ
description <p>Abstract</p> <p>Re-irradiation for recurrent gliomas has been discussed controversially in the past. This was mainly due to only marginal palliation while being associated with a high risk for side effects using conventional radiotherapy.</p> <p>With modern high-precision radiotherapy re-irradiation has become a more wide-spread, effective and well-tolerated treatment option. Besides external beam radiotherapy, a number of invasive and/or intraoperative radiation techniques have been evaluated in patients with recurrent gliomas.</p> <p>The present article is a review on the available methods in radiation oncology and summarizes results with respect to outcome and side effects in comparison to clinical results after neurosurgical resection or different chemotherapeutic approaches.</p>
first_indexed 2024-12-21T21:54:03Z
format Article
id doaj.art-1535c237129d437983a3ed64e9cacba1
institution Directory Open Access Journal
issn 1471-2407
language English
last_indexed 2024-12-21T21:54:03Z
publishDate 2007-08-01
publisher BMC
record_format Article
series BMC Cancer
spelling doaj.art-1535c237129d437983a3ed64e9cacba12022-12-21T18:49:01ZengBMCBMC Cancer1471-24072007-08-017116710.1186/1471-2407-7-167Radiotherapeutic alternatives for previously irradiated recurrent gliomasSchulz-Ertner DanielaDebus JürgenCombs Stephanie E<p>Abstract</p> <p>Re-irradiation for recurrent gliomas has been discussed controversially in the past. This was mainly due to only marginal palliation while being associated with a high risk for side effects using conventional radiotherapy.</p> <p>With modern high-precision radiotherapy re-irradiation has become a more wide-spread, effective and well-tolerated treatment option. Besides external beam radiotherapy, a number of invasive and/or intraoperative radiation techniques have been evaluated in patients with recurrent gliomas.</p> <p>The present article is a review on the available methods in radiation oncology and summarizes results with respect to outcome and side effects in comparison to clinical results after neurosurgical resection or different chemotherapeutic approaches.</p>http://www.biomedcentral.com/1471-2407/7/167
spellingShingle Schulz-Ertner Daniela
Debus Jürgen
Combs Stephanie E
Radiotherapeutic alternatives for previously irradiated recurrent gliomas
BMC Cancer
title Radiotherapeutic alternatives for previously irradiated recurrent gliomas
title_full Radiotherapeutic alternatives for previously irradiated recurrent gliomas
title_fullStr Radiotherapeutic alternatives for previously irradiated recurrent gliomas
title_full_unstemmed Radiotherapeutic alternatives for previously irradiated recurrent gliomas
title_short Radiotherapeutic alternatives for previously irradiated recurrent gliomas
title_sort radiotherapeutic alternatives for previously irradiated recurrent gliomas
url http://www.biomedcentral.com/1471-2407/7/167
work_keys_str_mv AT schulzertnerdaniela radiotherapeuticalternativesforpreviouslyirradiatedrecurrentgliomas
AT debusjurgen radiotherapeuticalternativesforpreviouslyirradiatedrecurrentgliomas
AT combsstephaniee radiotherapeuticalternativesforpreviouslyirradiatedrecurrentgliomas