Interleukin-10 rs2227307 and CXCR2 rs1126579 polymorphisms modulate the predisposition to septic shock

Interleukin-10 rs2227307 and CXCR2 rs1126579 polymorphisms modulate the predisposition to septic shock

Despite major improvements in its treatment and diagnosis, sepsis is still a leading cause of death and admittance to the intensive care unit (ICU). Failure to identify patients at high risk of developing septic shock contributes to an increase in the sepsis burden and rapid molecular tests are curr...

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Bibliographic Details
Main Authors: Cristina Padre Cardoso, Argenil José de Assis de Oliveira, Fernando Antônio Botoni, Isabela Cristina Porto Rezende, Jose Carlos Alves-Filho, Fernando de Queiroz Cunha, Juliana de Assis Silva Gomes Estanislau, Luiz Alexandre Viana Magno, Fabricio Rios-Santos
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2015-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
sepsis
septic shock
biomarkers
polymorphisms
inflammation
intensive care unit
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000400453&lng=en&tlng=en

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