A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts

A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts

<p>Abstract</p> <p>Background</p> <p>The p38α mitogen-activated protein kinase (MAPK) is a critical mediator of myoblast differentiation, and does so in part through the phosphorylation and regulation of several transcription factors and chromatin remodelling proteins....

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Bibliographic Details
Main Authors: Knight James DR, Tian Ruijun, Lee Robin EC, Wang Fangjun, Beauvais Ariane, Zou Hanfa, Megeney Lynn A, Gingras Anne-Claude, Pawson Tony, Figeys Daniel, Kothary Rashmi
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Skeletal Muscle
Subjects:
differentiation
FSBA
kinase assay
mitogen-activated protein kinase
myoblast
p38
phosphorylation
quantitative MS
Online Access:http://www.skeletalmusclejournal.com/content/2/1/5

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