Transplantation of mesenchymal stem cells and their derivatives effectively promotes liver regeneration to attenuate acetaminophen-induced liver injury

Transplantation of mesenchymal stem cells and their derivatives effectively promotes liver regeneration to attenuate acetaminophen-induced liver injury

Abstract Acetaminophen (APAP)-induced injury is a common clinical phenomenon that not only occurs in a dose-dependent manner but also occurs in some idiosyncratic individuals in a dose-independent manner. APAP overdose generally results in acute liver injury via the initiation of oxidative stress, e...

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Bibliographic Details
Main Authors: Chenxia Hu, Lingfei Zhao, Zhongwen Wu, Lanjuan Li
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Stem Cell Research & Therapy
Subjects:
Acetaminophen
Liver injury
Liver transplantation
Mesenchymal stem cell
Liver failure
Online Access:http://link.springer.com/article/10.1186/s13287-020-01596-9

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