Exploring the Effects of Various Capping Agents on Zinc Sulfide Quantum Dot Characteristics and In‐vitro Fate
Abstract The choice of capping agents used during the synthesis process of quantum dots (QDs) can significantly influence their fate and fundamental properties. Hence, choosing an appropriate capping agent is a critical step in both synthesis and biomedical application of QDs. In this research, ZnS...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley-VCH
2023-10-01
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| Series: | ChemistryOpen |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/open.202300094 |
| _version_ | 1797649201750867968 |
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| author | Zohre Montaseri Prof. Ali Mohammad Tamaddon Dr. Mohammad Javad Raee Dr. Fakhrossadat Farvadi |
| author_facet | Zohre Montaseri Prof. Ali Mohammad Tamaddon Dr. Mohammad Javad Raee Dr. Fakhrossadat Farvadi |
| author_sort | Zohre Montaseri |
| collection | DOAJ |
| description | Abstract The choice of capping agents used during the synthesis process of quantum dots (QDs) can significantly influence their fate and fundamental properties. Hence, choosing an appropriate capping agent is a critical step in both synthesis and biomedical application of QDs. In this research, ZnS QDs were synthesized via chemical precipitation process and three commonly employed capping agents, namely mercaptoethanol (ME), mercaptoacetic acid (MAA), and cysteamine (CA), were used to stabilize the QDs. This study was aimed to examine how these capping agents impact the physicochemical and optical characteristics of ZnS QDs, as well as their interactions with biological systems. The findings revealed that the capping agents had considerable effects on the behavior and properties of ZnS QDs. MAA‐QD exhibited superior crystal lattice, smaller size, and significant quantum yield (QY). In contrast, CA‐QDs demonstrated the lowest QY and the highest tendency for aggregation. ME‐QDs exhibited intermediate characteristics, along with an acceptable level of cytotoxicity, rapid uptake by cells, and efficient escape from lysosomes. Consequently, it is advisable to select capping agents in accordance with the specific objectives of the research. |
| first_indexed | 2024-03-11T15:42:50Z |
| format | Article |
| id | doaj.art-153dbc7d86884cdbb555c6731cb0826e |
| institution | Directory Open Access Journal |
| issn | 2191-1363 |
| language | English |
| last_indexed | 2024-03-11T15:42:50Z |
| publishDate | 2023-10-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | ChemistryOpen |
| spelling | doaj.art-153dbc7d86884cdbb555c6731cb0826e2023-10-26T08:28:29ZengWiley-VCHChemistryOpen2191-13632023-10-011210n/an/a10.1002/open.202300094Exploring the Effects of Various Capping Agents on Zinc Sulfide Quantum Dot Characteristics and In‐vitro FateZohre Montaseri0Prof. Ali Mohammad Tamaddon1Dr. Mohammad Javad Raee2Dr. Fakhrossadat Farvadi3Center for Nanotechnology in Drug Delivery Shiraz University of Medical Sciences Shiraz IranCenter for Nanotechnology in Drug Delivery Shiraz University of Medical Sciences Shiraz IranCenter for Nanotechnology in Drug Delivery Shiraz University of Medical Sciences Shiraz IranCenter for Nanotechnology in Drug Delivery Shiraz University of Medical Sciences Shiraz IranAbstract The choice of capping agents used during the synthesis process of quantum dots (QDs) can significantly influence their fate and fundamental properties. Hence, choosing an appropriate capping agent is a critical step in both synthesis and biomedical application of QDs. In this research, ZnS QDs were synthesized via chemical precipitation process and three commonly employed capping agents, namely mercaptoethanol (ME), mercaptoacetic acid (MAA), and cysteamine (CA), were used to stabilize the QDs. This study was aimed to examine how these capping agents impact the physicochemical and optical characteristics of ZnS QDs, as well as their interactions with biological systems. The findings revealed that the capping agents had considerable effects on the behavior and properties of ZnS QDs. MAA‐QD exhibited superior crystal lattice, smaller size, and significant quantum yield (QY). In contrast, CA‐QDs demonstrated the lowest QY and the highest tendency for aggregation. ME‐QDs exhibited intermediate characteristics, along with an acceptable level of cytotoxicity, rapid uptake by cells, and efficient escape from lysosomes. Consequently, it is advisable to select capping agents in accordance with the specific objectives of the research.https://doi.org/10.1002/open.202300094quantum dotcolloidal stabilizationcapping agentstabilizing agentnanoparticle fate |
| spellingShingle | Zohre Montaseri Prof. Ali Mohammad Tamaddon Dr. Mohammad Javad Raee Dr. Fakhrossadat Farvadi Exploring the Effects of Various Capping Agents on Zinc Sulfide Quantum Dot Characteristics and In‐vitro Fate ChemistryOpen quantum dot colloidal stabilization capping agent stabilizing agent nanoparticle fate |
| title | Exploring the Effects of Various Capping Agents on Zinc Sulfide Quantum Dot Characteristics and In‐vitro Fate |
| title_full | Exploring the Effects of Various Capping Agents on Zinc Sulfide Quantum Dot Characteristics and In‐vitro Fate |
| title_fullStr | Exploring the Effects of Various Capping Agents on Zinc Sulfide Quantum Dot Characteristics and In‐vitro Fate |
| title_full_unstemmed | Exploring the Effects of Various Capping Agents on Zinc Sulfide Quantum Dot Characteristics and In‐vitro Fate |
| title_short | Exploring the Effects of Various Capping Agents on Zinc Sulfide Quantum Dot Characteristics and In‐vitro Fate |
| title_sort | exploring the effects of various capping agents on zinc sulfide quantum dot characteristics and in vitro fate |
| topic | quantum dot colloidal stabilization capping agent stabilizing agent nanoparticle fate |
| url | https://doi.org/10.1002/open.202300094 |
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