Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection

The scale of the cosmetic market is increasing every day. There are many safety risks to cosmetics, but they benefit people at the same time. The skin can become red, swollen, itchy, chronically toxic, and senescent due to the misuse of cosmetics, triggering skin injuries, with contact dermatitis be...

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Main Authors: Min Wang, Linfeng Zhang, Haojie Hao, Muyang Yan, Ziying Zhu
Format: Article
Language:English
Published: SAGE Publishing 2024-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897241235464
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author Min Wang
Linfeng Zhang
Haojie Hao
Muyang Yan
Ziying Zhu
author_facet Min Wang
Linfeng Zhang
Haojie Hao
Muyang Yan
Ziying Zhu
author_sort Min Wang
collection DOAJ
description The scale of the cosmetic market is increasing every day. There are many safety risks to cosmetics, but they benefit people at the same time. The skin can become red, swollen, itchy, chronically toxic, and senescent due to the misuse of cosmetics, triggering skin injuries, with contact dermatitis being the most common. Therefore, there is an urgent need for a system that can scientifically and rationally detect the composition and perform a toxicological assessment of cosmetic products. Traditional detection methods rely on instrumentation and method selection, which are less sensitive and more complex to perform. Engineered skin tissue has emerged with the advent of tissue engineering technology as an emerging bioengineering technology. The ideal engineered skin tissue is the basis for building good in vitro structures and physiological functions in this field. This review introduces the existing cosmetic testing and toxicological evaluation methods, the current development status, and the types and characteristics of engineered skin tissue. The application of engineered skin tissue in the field of cosmetic composition detection and toxicological evaluation, as well as the different types of tissue engineering scaffold materials and three-dimensional (3D) organoid preparation approaches, is highlighted in this review to provide methods and ideas for constructing the next engineered skin tissue for cosmetic raw material component analysis and toxicological evaluation.
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spelling doaj.art-153efffaee894f988242ea1a705d01e32024-03-17T10:03:18ZengSAGE PublishingCell Transplantation1555-38922024-03-013310.1177/09636897241235464Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology DetectionMin Wang0Linfeng Zhang1Haojie Hao2Muyang Yan3Ziying Zhu4College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, ChinaCollege of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, ChinaThe First Medical Center, Chinese People’s Liberation Army General Hospital, Beijing, ChinaThe First Medical Center, Chinese People’s Liberation Army General Hospital, Beijing, ChinaThe First Medical Center, Chinese People’s Liberation Army General Hospital, Beijing, ChinaThe scale of the cosmetic market is increasing every day. There are many safety risks to cosmetics, but they benefit people at the same time. The skin can become red, swollen, itchy, chronically toxic, and senescent due to the misuse of cosmetics, triggering skin injuries, with contact dermatitis being the most common. Therefore, there is an urgent need for a system that can scientifically and rationally detect the composition and perform a toxicological assessment of cosmetic products. Traditional detection methods rely on instrumentation and method selection, which are less sensitive and more complex to perform. Engineered skin tissue has emerged with the advent of tissue engineering technology as an emerging bioengineering technology. The ideal engineered skin tissue is the basis for building good in vitro structures and physiological functions in this field. This review introduces the existing cosmetic testing and toxicological evaluation methods, the current development status, and the types and characteristics of engineered skin tissue. The application of engineered skin tissue in the field of cosmetic composition detection and toxicological evaluation, as well as the different types of tissue engineering scaffold materials and three-dimensional (3D) organoid preparation approaches, is highlighted in this review to provide methods and ideas for constructing the next engineered skin tissue for cosmetic raw material component analysis and toxicological evaluation.https://doi.org/10.1177/09636897241235464
spellingShingle Min Wang
Linfeng Zhang
Haojie Hao
Muyang Yan
Ziying Zhu
Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
Cell Transplantation
title Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
title_full Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
title_fullStr Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
title_full_unstemmed Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
title_short Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
title_sort applications of engineered skin tissue for cosmetic component and toxicology detection
url https://doi.org/10.1177/09636897241235464
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AT haojiehao applicationsofengineeredskintissueforcosmeticcomponentandtoxicologydetection
AT muyangyan applicationsofengineeredskintissueforcosmeticcomponentandtoxicologydetection
AT ziyingzhu applicationsofengineeredskintissueforcosmeticcomponentandtoxicologydetection