| Summary: | Introduction. Sleep disorders and psychological disturbances are common in
end-stage renal disease (ESRD) patients. However, despite their frequency and
importance, such conditions often go unnoticed, since all patients do not
clearly manifest fully expressed symptoms. Objective. This study aimed to
determine the prevalence of depression and poor sleep quality and to examine
the association between these disorders and demographic, clinical and
treatment-related characteristics of ESRD patients on hemodialysis (HD).
Methods. The study included 222 patients (132 men and 90 women), mean age
57.3±11.9 years, from 3 HD centers in Central Serbia, which provided us with
biochemical parameters and demographic data. Sleep quality and depression
were assessed using the Pittsburgh Sleep Quality Index (PSQI) and Beck
Depression Inventory (BDI), respectively. Results. The average BDI was
16.1±11.3. Depressed patients were significantly older (p=0.041), had a
significantly lower dialysis adequacy (p=0.027) and a significantly worse
quality of sleep (p<0.001), while they did not show significant difference as
regarding sex, employment, marital status, comorbidities, dialysis type,
dialysis vintage, shift and laboratory parameters. The average PSQI was
7.8±4.5 and 64.2% of patients were poor sleepers. Poor sleepers were
significantly older (p=0.002), they were more often females (p=0.027) and had
a significantly higher BDI (p<0.001), while other investigated variables were
not correlated with sleep quality. A statistically significant positive
correlation was found between BDI and PSQI (r=0.604; p<0.001). Conclusion.
Depression and poor sleep quality are frequent and interrelated among HD
patients.
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