Effects of High Tibial Osteotomy Combined with Arthroscopy on Pain and Inflammation Markers in Patients with Medial Knee Osteoarthritis
Objective To investigate the effect of high tibial osteotomy (HTO) combined with arthroscopy on pain and serum inflammatory factors in patients with medial knee osteoarthritis. Methods A total of 82 patients with medial knee osteoarthritis were admitted to our hospital. They were randomly divided in...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2022-04-01
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| Series: | Journal of Investigative Surgery |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/08941939.2021.1931576 |
| Summary: | Objective To investigate the effect of high tibial osteotomy (HTO) combined with arthroscopy on pain and serum inflammatory factors in patients with medial knee osteoarthritis. Methods A total of 82 patients with medial knee osteoarthritis were admitted to our hospital. They were randomly divided into HTO-arthroscopy (HTO-A, treated with HTO combined with arthroscopy) group or HTO group (treated with HTO). The pain degree and serum inflammatory factors were primary outcomes. Moreover, the operation time, intraoperative blood loss, hospital stay, postoperative complications, hip-knee-ankle angle (HKA), medial proximal tibial angle (MPTA), posterior tibial slope angle, function of the knee joint [based on American knee society knee score (KSS) and hospital for special surgery knee score (HSS)] were also collected. Results The hospital stay in HTO-A group was significantly lower than that in the HTO group (P < 0.05). On 1 month, 3 months and 6 months after operation, the KSS and HSS scores were higher and the pain degree was lower in HTO-A group than those in HTO group (P < 0.05). The operations of all patients were successful, and during the 6-month follow-up, there were no complications occurred in both groups, such as nerve or vascular injury, incision infection, fracture nonunion or delayed union, internal fixation failure and deep vein thrombosis. Conclusion HTO combined with arthroscopy could shorten the hospital stay, and effectively relieve pain degree and reduce serum inflammatory factors in patients with medial knee osteoarthritis, which is worthy of further clinical application. |
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| ISSN: | 0894-1939 1521-0553 |