Choroidal thickness in Malaysian eyes with full-thickness macular holes
AIM: To compare choroidal thickness at the macula in eyes with unilateral idiopathic full-thickness macular holes(FTMH)with that of unaffected fellow eyes, and eyes of normal control patients.<p>METHODS: Cross-sectional study. Thirty patients with unilateral idiopathic FTMH and thirty age, sex...
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Press of International Journal of Ophthalmology (IJO PRESS)
2018-02-01
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| Series: | Guoji Yanke Zazhi |
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| Online Access: | http://www.ijo.cn/cn_publish/2018/3/201803001.pdf |
| _version_ | 1818675529844260864 |
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| author | Chew Y Tan Selva R Vengadasalam Amir Samsudin Nurliza Khaliddin |
| author_facet | Chew Y Tan Selva R Vengadasalam Amir Samsudin Nurliza Khaliddin |
| author_sort | Chew Y Tan |
| collection | DOAJ |
| description | AIM: To compare choroidal thickness at the macula in eyes with unilateral idiopathic full-thickness macular holes(FTMH)with that of unaffected fellow eyes, and eyes of normal control patients.<p>METHODS: Cross-sectional study. Thirty patients with unilateral idiopathic FTMH and thirty age, sex, and race-matched controls were recruited. Axial lengths were measured using laser interferometry. Enhanced depth imaging optical coherence tomography images were obtained using Heidelberg spectral-domain optical coherence tomography. Choroidal thickness was measured at the fovea, and at 1 mm and 2 mm nasally, temporally, superiorly and inferiorly from the center of the fovea. Statistical analysis was performed using independent and paired <i>t</i>-tests, chi-square tests, and Pearson correlation tests(<i>P</i><0.05).<p>RESULTS: The mean subfoveal choroidal thickness was 201.0±44.0 μm in the FTMH group, 225.3±51.4 μm in the fellow eye group and 262.3±70.3 μm in the control group. The choroid was thinner in FTMH eyes at all locations when compared to control eyes(<i>P</i><0.05). The fellow eye group also had thinner choroids than the control group at all locations except at 1 mm and 2 mm nasal to the fovea(<i>P</i><0.05). Choroidal thickness in the FTMH group was lower than in the fellow eye group, but the differences were not statistically significant(<i>P</i>>0.05). Choroidal thickness was generally highest subfoveally and lowest nasally. Subfoveal choroidal thickness was negatively correlated with age(<i>r</i>=-0.278, <i>P</i>=0.032), and axial length(<i>r</i>=-0.328, <i>P</i>=0.011).<p>CONCLUSION: Choroidal thickness is lower in both eyes of patients with unilateral FTMH compared to healthy control eyes. |
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| format | Article |
| id | doaj.art-1550b4bbc8ba4fd796a05d70d7ba31e9 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-17T08:29:02Z |
| publishDate | 2018-02-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
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| series | Guoji Yanke Zazhi |
| spelling | doaj.art-1550b4bbc8ba4fd796a05d70d7ba31e92022-12-21T21:56:39ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232018-02-0118340140510.3980/j.issn.1672-5123.2018.3.01Choroidal thickness in Malaysian eyes with full-thickness macular holesChew Y Tan0Selva R Vengadasalam1Amir Samsudin2Nurliza Khaliddin3Department of Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia; Department of Ophthalmology, Selayang Hospital, Selangor 68100, MalaysiaDepartment of Ophthalmology, Selayang Hospital, Selangor 68100, MalaysiaDepartment of Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, MalaysiaDepartment of Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, MalaysiaAIM: To compare choroidal thickness at the macula in eyes with unilateral idiopathic full-thickness macular holes(FTMH)with that of unaffected fellow eyes, and eyes of normal control patients.<p>METHODS: Cross-sectional study. Thirty patients with unilateral idiopathic FTMH and thirty age, sex, and race-matched controls were recruited. Axial lengths were measured using laser interferometry. Enhanced depth imaging optical coherence tomography images were obtained using Heidelberg spectral-domain optical coherence tomography. Choroidal thickness was measured at the fovea, and at 1 mm and 2 mm nasally, temporally, superiorly and inferiorly from the center of the fovea. Statistical analysis was performed using independent and paired <i>t</i>-tests, chi-square tests, and Pearson correlation tests(<i>P</i><0.05).<p>RESULTS: The mean subfoveal choroidal thickness was 201.0±44.0 μm in the FTMH group, 225.3±51.4 μm in the fellow eye group and 262.3±70.3 μm in the control group. The choroid was thinner in FTMH eyes at all locations when compared to control eyes(<i>P</i><0.05). The fellow eye group also had thinner choroids than the control group at all locations except at 1 mm and 2 mm nasal to the fovea(<i>P</i><0.05). Choroidal thickness in the FTMH group was lower than in the fellow eye group, but the differences were not statistically significant(<i>P</i>>0.05). Choroidal thickness was generally highest subfoveally and lowest nasally. Subfoveal choroidal thickness was negatively correlated with age(<i>r</i>=-0.278, <i>P</i>=0.032), and axial length(<i>r</i>=-0.328, <i>P</i>=0.011).<p>CONCLUSION: Choroidal thickness is lower in both eyes of patients with unilateral FTMH compared to healthy control eyes.http://www.ijo.cn/cn_publish/2018/3/201803001.pdfchoroidal thickness; macular holes; optical coherence tomography; spectral-domain; enhanced depth imaging; Heidelbergchoroidal thicknessmacular holesoptical coherence tomographyspectral-domainenhanced depth imagingHeidelberg |
| spellingShingle | Chew Y Tan Selva R Vengadasalam Amir Samsudin Nurliza Khaliddin Choroidal thickness in Malaysian eyes with full-thickness macular holes Guoji Yanke Zazhi choroidal thickness; macular holes; optical coherence tomography; spectral-domain; enhanced depth imaging; Heidelberg choroidal thickness macular holes optical coherence tomography spectral-domain enhanced depth imaging Heidelberg |
| title | Choroidal thickness in Malaysian eyes with full-thickness macular holes |
| title_full | Choroidal thickness in Malaysian eyes with full-thickness macular holes |
| title_fullStr | Choroidal thickness in Malaysian eyes with full-thickness macular holes |
| title_full_unstemmed | Choroidal thickness in Malaysian eyes with full-thickness macular holes |
| title_short | Choroidal thickness in Malaysian eyes with full-thickness macular holes |
| title_sort | choroidal thickness in malaysian eyes with full thickness macular holes |
| topic | choroidal thickness; macular holes; optical coherence tomography; spectral-domain; enhanced depth imaging; Heidelberg choroidal thickness macular holes optical coherence tomography spectral-domain enhanced depth imaging Heidelberg |
| url | http://www.ijo.cn/cn_publish/2018/3/201803001.pdf |
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