Natural Herbal Non-Opioid Topical Pain Relievers—Comparison with Traditional Therapy
Pain is the predominant symptom of many clinical diseases and is frequently associated with neurological and musculoskeletal problems. Chronic pain is frequent in the elderly, causing suffering, disability, social isolation, and increased healthcare expenses. Chronic pain medication is often ineffec...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Pharmaceutics |
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| Online Access: | https://www.mdpi.com/1999-4923/14/12/2648 |
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| author | Dalia M. Kopustinskiene Urte Bernatonyte Yuliia Maslii Nataliia Herbina Jurga Bernatoniene |
| author_facet | Dalia M. Kopustinskiene Urte Bernatonyte Yuliia Maslii Nataliia Herbina Jurga Bernatoniene |
| author_sort | Dalia M. Kopustinskiene |
| collection | DOAJ |
| description | Pain is the predominant symptom of many clinical diseases and is frequently associated with neurological and musculoskeletal problems. Chronic pain is frequent in the elderly, causing suffering, disability, social isolation, and increased healthcare expenses. Chronic pain medication is often ineffective and has many side effects. Nonsteroidal over-the-counter and prescription drugs are frequently recommended as first-line therapies for pain control; however, long-term safety issues must not be neglected. Herbs and nutritional supplements may be a safer and more effective alternative to nonsteroidal pharmaceuticals for pain management, especially when used long-term. Recently, topical analgesic therapies have gained attention as an innovative approach due to their sufficient efficacy and comparatively fewer systemic side effects and drug–drug interactions. In this paper, we overview the main natural herbal pain relievers, their efficacy and safety, and their potential use as topical agents for pain control. Although herbal-derived medications are not appropriate for providing quick relief for acute pain problems, they could be used as potent alternative remedies in managing chronic persistent pain with minimal side effects. |
| first_indexed | 2024-03-09T15:58:04Z |
| format | Article |
| id | doaj.art-1551de6bf43347ce98f4512f377fdc06 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-09T15:58:04Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-1551de6bf43347ce98f4512f377fdc062023-11-24T17:19:36ZengMDPI AGPharmaceutics1999-49232022-11-011412264810.3390/pharmaceutics14122648Natural Herbal Non-Opioid Topical Pain Relievers—Comparison with Traditional TherapyDalia M. Kopustinskiene0Urte Bernatonyte1Yuliia Maslii2Nataliia Herbina3Jurga Bernatoniene4Institute of Pharmaceutical Technologies, Faculty of Pharmacy, Medical Academy, Lithuanian University of Health Sciences, Sukileliu pr. 13, LT-50161 Kaunas, LithuaniaFaculty of Pharmacy, Medical Academy, Lithuanian University of Health Sciences, Sukileliu pr. 13, LT-50161 Kaunas, LithuaniaDepartment of Drug Technology and Social Pharmacy, Faculty of Pharmacy, Medical Academy, Lithuanian University of Health Sciences, Sukileliu pr. 13, LT-50161 Kaunas, LithuaniaDepartment of Drug Technology and Social Pharmacy, Faculty of Pharmacy, Medical Academy, Lithuanian University of Health Sciences, Sukileliu pr. 13, LT-50161 Kaunas, LithuaniaInstitute of Pharmaceutical Technologies, Faculty of Pharmacy, Medical Academy, Lithuanian University of Health Sciences, Sukileliu pr. 13, LT-50161 Kaunas, LithuaniaPain is the predominant symptom of many clinical diseases and is frequently associated with neurological and musculoskeletal problems. Chronic pain is frequent in the elderly, causing suffering, disability, social isolation, and increased healthcare expenses. Chronic pain medication is often ineffective and has many side effects. Nonsteroidal over-the-counter and prescription drugs are frequently recommended as first-line therapies for pain control; however, long-term safety issues must not be neglected. Herbs and nutritional supplements may be a safer and more effective alternative to nonsteroidal pharmaceuticals for pain management, especially when used long-term. Recently, topical analgesic therapies have gained attention as an innovative approach due to their sufficient efficacy and comparatively fewer systemic side effects and drug–drug interactions. In this paper, we overview the main natural herbal pain relievers, their efficacy and safety, and their potential use as topical agents for pain control. Although herbal-derived medications are not appropriate for providing quick relief for acute pain problems, they could be used as potent alternative remedies in managing chronic persistent pain with minimal side effects.https://www.mdpi.com/1999-4923/14/12/2648pain controlalternative medicinetherapy |
| spellingShingle | Dalia M. Kopustinskiene Urte Bernatonyte Yuliia Maslii Nataliia Herbina Jurga Bernatoniene Natural Herbal Non-Opioid Topical Pain Relievers—Comparison with Traditional Therapy Pharmaceutics pain control alternative medicine therapy |
| title | Natural Herbal Non-Opioid Topical Pain Relievers—Comparison with Traditional Therapy |
| title_full | Natural Herbal Non-Opioid Topical Pain Relievers—Comparison with Traditional Therapy |
| title_fullStr | Natural Herbal Non-Opioid Topical Pain Relievers—Comparison with Traditional Therapy |
| title_full_unstemmed | Natural Herbal Non-Opioid Topical Pain Relievers—Comparison with Traditional Therapy |
| title_short | Natural Herbal Non-Opioid Topical Pain Relievers—Comparison with Traditional Therapy |
| title_sort | natural herbal non opioid topical pain relievers comparison with traditional therapy |
| topic | pain control alternative medicine therapy |
| url | https://www.mdpi.com/1999-4923/14/12/2648 |
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