Toxicity of manufactured copper nanoparticles - A review
<span class="CharOverride-21">The health effects of nanoparticles (NPs) are raising considerable and growing concerns from the public and government around the world. Nano-metals are new forms of metal with special properties, but are characterized by having a particle size of less t...
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| Format: | Article |
| Language: | English |
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Iranian Society of Nanomedicine
2018-01-01
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| Series: | Nanomedicine Research Journal |
| Subjects: | |
| Online Access: | http://www.nanomedicine-rj.com/article_31894_e3ee90a511d47a059ad7196b1fd44f8c.pdf |
| _version_ | 1818156870894878720 |
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| author | Marzie Hejazy Mohammad Kazem Koohi Adele Bassiri Mohamad Pour Davood Najafi |
| author_facet | Marzie Hejazy Mohammad Kazem Koohi Adele Bassiri Mohamad Pour Davood Najafi |
| author_sort | Marzie Hejazy |
| collection | DOAJ |
| description | <span class="CharOverride-21">The health effects of nanoparticles (NPs) are raising considerable and growing concerns from the public and government around the world. Nano-metals are new forms of metal with special properties, but are characterized by having a particle size of less than 100 nm. Copper is an essential trace element and its deficiency leads to different diseases in humans. In general, copper NPs have been reported among the most toxic nanomaterials in mammals. The toxicity of nano-copper depends on sex. The increase in the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) plays an important role in copper-induced organic dysfunction.</span><span class="CharOverride-21">In this review, we will not only summarize the tissues toxicology induced by nano-copper, but also we will discuss the functions of ROS and RNS in the pathogenesis and toxicity in different organs, DNA damage as a result of oxidative stress, changes in Blood biochemical indexes, and the mechanism of the nano-copper induced apoptosis.</span> |
| first_indexed | 2024-12-11T15:05:10Z |
| format | Article |
| id | doaj.art-155422dac7e9497ca094dce5b1d9a56a |
| institution | Directory Open Access Journal |
| issn | 2476-3489 2476-7123 |
| language | English |
| last_indexed | 2024-12-11T15:05:10Z |
| publishDate | 2018-01-01 |
| publisher | Iranian Society of Nanomedicine |
| record_format | Article |
| series | Nanomedicine Research Journal |
| spelling | doaj.art-155422dac7e9497ca094dce5b1d9a56a2022-12-22T01:00:58ZengIranian Society of NanomedicineNanomedicine Research Journal2476-34892476-71232018-01-01311910.22034/nmrj.2018.01.00131894Toxicity of manufactured copper nanoparticles - A reviewMarzie Hejazy0Mohammad Kazem Koohi1Adele Bassiri Mohamad Pour2Davood Najafi3Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, IranBasic Science Department, Faculty of Veterinary Medicine, University of Tehran, Tehran, IranFaculty of Veterinary Medicine, Islamic Azad University of Tabriz, Tabriz, IranFaculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran<span class="CharOverride-21">The health effects of nanoparticles (NPs) are raising considerable and growing concerns from the public and government around the world. Nano-metals are new forms of metal with special properties, but are characterized by having a particle size of less than 100 nm. Copper is an essential trace element and its deficiency leads to different diseases in humans. In general, copper NPs have been reported among the most toxic nanomaterials in mammals. The toxicity of nano-copper depends on sex. The increase in the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) plays an important role in copper-induced organic dysfunction.</span><span class="CharOverride-21">In this review, we will not only summarize the tissues toxicology induced by nano-copper, but also we will discuss the functions of ROS and RNS in the pathogenesis and toxicity in different organs, DNA damage as a result of oxidative stress, changes in Blood biochemical indexes, and the mechanism of the nano-copper induced apoptosis.</span>http://www.nanomedicine-rj.com/article_31894_e3ee90a511d47a059ad7196b1fd44f8c.pdfapoptosisnano-coppernanoparticlesrnsrostoxicity |
| spellingShingle | Marzie Hejazy Mohammad Kazem Koohi Adele Bassiri Mohamad Pour Davood Najafi Toxicity of manufactured copper nanoparticles - A review Nanomedicine Research Journal apoptosis nano-copper nanoparticles rns ros toxicity |
| title | Toxicity of manufactured copper nanoparticles - A review |
| title_full | Toxicity of manufactured copper nanoparticles - A review |
| title_fullStr | Toxicity of manufactured copper nanoparticles - A review |
| title_full_unstemmed | Toxicity of manufactured copper nanoparticles - A review |
| title_short | Toxicity of manufactured copper nanoparticles - A review |
| title_sort | toxicity of manufactured copper nanoparticles a review |
| topic | apoptosis nano-copper nanoparticles rns ros toxicity |
| url | http://www.nanomedicine-rj.com/article_31894_e3ee90a511d47a059ad7196b1fd44f8c.pdf |
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