Obesity-induced elevated palmitic acid promotes inflammation and glucose metabolism disorders through GPRs/NF-κB/KLF7 pathway

Abstract Objective Our previous results have shown that obesity-induced excessive palmitic acid (PA) can promote the expression of KLF7, which plays a vital role in regulation of inflammation, glucose metabolism. But the exact mechanism of PA up-regulating the expression of KLF7 is not clear yet. Th...

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Bibliographic Details
Main Authors: Tongtong Qiu, Xin Yang, Jingzhou Wang, Chongge Pan, Xiaolong Chu, Jianyu Xiong, Jianxin Xie, Yongsheng Chang, Cuizhe Wang, Jun Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Nutrition & Diabetes
Online Access:https://doi.org/10.1038/s41387-022-00202-6