The Prevalence of Fallopian Tube Occlusion in Women with Polycystic Ovary Syndrome Seems Similar to Non-Subfertile Women: A Retrospective Cohort Study
There are limited data on how non-infectious risk factors influence tubal patency in women with subfertility. With hormonal shifts influencing tubal secretions, it has been argued that subfertile women with polycystic ovary syndrome (PCOS) have lower tubal patency. In a retrospective study, 216 wome...
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| Format: | Article |
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MDPI AG
2022-09-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/19/5610 |
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| author | Stefan Ghobrial John Preston Parry Iris Holzer Judith Aschauer Clara Selzer Andreas Brezina Samir Helmy-Bader Johannes Ott |
| author_facet | Stefan Ghobrial John Preston Parry Iris Holzer Judith Aschauer Clara Selzer Andreas Brezina Samir Helmy-Bader Johannes Ott |
| author_sort | Stefan Ghobrial |
| collection | DOAJ |
| description | There are limited data on how non-infectious risk factors influence tubal patency in women with subfertility. With hormonal shifts influencing tubal secretions, it has been argued that subfertile women with polycystic ovary syndrome (PCOS) have lower tubal patency. In a retrospective study, 216 women, who underwent diagnostic evaluation for PCOS and infertility, were included. Fallopian tube patency was tested using HSG, HyCoSy, and laparoscopic chromopertubation in 171 (79.2%), 28 (13.0%), and 17 (7.9%), respectively. Bilateral patency was found in 193 women (89.4%), unilateral patency in 13 (6.0%) and bilateral occlusion in 10 (4.6%) patients. Women with PCOS phenotypes C (odds ratio, OR 0.179, 95% CI: 0.039–0.828) and D (OR 0.256, 95% CI: 0.069–0.947) demonstrated lower risks for Fallopian tube occlusion. In conclusion, our data suggest that about 5% of infertile women with PCOS also have bilateral tubal occlusion, which seems similar to the rate in non-subfertile women. With 11% of participants having unilateral or bilateral tubal occlusion, this should reassure women with PCOS that their hormonal challenges do not seem to increase their risk for tubal factor subfertility. |
| first_indexed | 2024-03-09T21:35:01Z |
| format | Article |
| id | doaj.art-156a66c589f542fa9d3885e4c8bd6a94 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T21:35:01Z |
| publishDate | 2022-09-01 |
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| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-156a66c589f542fa9d3885e4c8bd6a942023-11-23T20:45:52ZengMDPI AGJournal of Clinical Medicine2077-03832022-09-011119561010.3390/jcm11195610The Prevalence of Fallopian Tube Occlusion in Women with Polycystic Ovary Syndrome Seems Similar to Non-Subfertile Women: A Retrospective Cohort StudyStefan Ghobrial0John Preston Parry1Iris Holzer2Judith Aschauer3Clara Selzer4Andreas Brezina5Samir Helmy-Bader6Johannes Ott7Clinical Division of Gynecologic Endocrinology and Reproductive Medicine, Medical University of Vienna, 1090 Vienna, AustriaParryscope and Positive Steps Fertility, Madison, WI 39110, USAClinical Division of Gynecologic Endocrinology and Reproductive Medicine, Medical University of Vienna, 1090 Vienna, AustriaClinical Division of Gynecologic Endocrinology and Reproductive Medicine, Medical University of Vienna, 1090 Vienna, AustriaClinical Division of Gynecologic Endocrinology and Reproductive Medicine, Medical University of Vienna, 1090 Vienna, AustriaPrivatklinik Goldenes Kreuz, 1090 Vienna, AustriaClinical Division of General Gynecology and Gynecologic Oncology, Medical University of Vienna, 1090 Vienna, AustriaClinical Division of Gynecologic Endocrinology and Reproductive Medicine, Medical University of Vienna, 1090 Vienna, AustriaThere are limited data on how non-infectious risk factors influence tubal patency in women with subfertility. With hormonal shifts influencing tubal secretions, it has been argued that subfertile women with polycystic ovary syndrome (PCOS) have lower tubal patency. In a retrospective study, 216 women, who underwent diagnostic evaluation for PCOS and infertility, were included. Fallopian tube patency was tested using HSG, HyCoSy, and laparoscopic chromopertubation in 171 (79.2%), 28 (13.0%), and 17 (7.9%), respectively. Bilateral patency was found in 193 women (89.4%), unilateral patency in 13 (6.0%) and bilateral occlusion in 10 (4.6%) patients. Women with PCOS phenotypes C (odds ratio, OR 0.179, 95% CI: 0.039–0.828) and D (OR 0.256, 95% CI: 0.069–0.947) demonstrated lower risks for Fallopian tube occlusion. In conclusion, our data suggest that about 5% of infertile women with PCOS also have bilateral tubal occlusion, which seems similar to the rate in non-subfertile women. With 11% of participants having unilateral or bilateral tubal occlusion, this should reassure women with PCOS that their hormonal challenges do not seem to increase their risk for tubal factor subfertility.https://www.mdpi.com/2077-0383/11/19/5610PCOSfallopian tubefertilitytubal occlusionprevalence |
| spellingShingle | Stefan Ghobrial John Preston Parry Iris Holzer Judith Aschauer Clara Selzer Andreas Brezina Samir Helmy-Bader Johannes Ott The Prevalence of Fallopian Tube Occlusion in Women with Polycystic Ovary Syndrome Seems Similar to Non-Subfertile Women: A Retrospective Cohort Study Journal of Clinical Medicine PCOS fallopian tube fertility tubal occlusion prevalence |
| title | The Prevalence of Fallopian Tube Occlusion in Women with Polycystic Ovary Syndrome Seems Similar to Non-Subfertile Women: A Retrospective Cohort Study |
| title_full | The Prevalence of Fallopian Tube Occlusion in Women with Polycystic Ovary Syndrome Seems Similar to Non-Subfertile Women: A Retrospective Cohort Study |
| title_fullStr | The Prevalence of Fallopian Tube Occlusion in Women with Polycystic Ovary Syndrome Seems Similar to Non-Subfertile Women: A Retrospective Cohort Study |
| title_full_unstemmed | The Prevalence of Fallopian Tube Occlusion in Women with Polycystic Ovary Syndrome Seems Similar to Non-Subfertile Women: A Retrospective Cohort Study |
| title_short | The Prevalence of Fallopian Tube Occlusion in Women with Polycystic Ovary Syndrome Seems Similar to Non-Subfertile Women: A Retrospective Cohort Study |
| title_sort | prevalence of fallopian tube occlusion in women with polycystic ovary syndrome seems similar to non subfertile women a retrospective cohort study |
| topic | PCOS fallopian tube fertility tubal occlusion prevalence |
| url | https://www.mdpi.com/2077-0383/11/19/5610 |
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