Argovit™ Silver Nanoparticles Effects on <i>Allium cepa</i>: Plant Growth Promotion without Cyto Genotoxic Damage
Due to their antibacterial and antiviral effects, silver nanoparticles (AgNP) are one of the most widely used nanomaterials worldwide in various industries, e.g., in textiles, cosmetics and biomedical-related products. Unfortunately, the lack of complete physicochemical characterization and the vari...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-07-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/10/7/1386 |
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| author | Francisco Casillas-Figueroa María Evarista Arellano-García Claudia Leyva-Aguilera Balam Ruíz-Ruíz Roberto Luna Vázquez-Gómez Patricia Radilla-Chávez Rocío Alejandra Chávez-Santoscoy Alexey Pestryakov Yanis Toledano-Magaña Juan Carlos García-Ramos Nina Bogdanchikova |
| author_facet | Francisco Casillas-Figueroa María Evarista Arellano-García Claudia Leyva-Aguilera Balam Ruíz-Ruíz Roberto Luna Vázquez-Gómez Patricia Radilla-Chávez Rocío Alejandra Chávez-Santoscoy Alexey Pestryakov Yanis Toledano-Magaña Juan Carlos García-Ramos Nina Bogdanchikova |
| author_sort | Francisco Casillas-Figueroa |
| collection | DOAJ |
| description | Due to their antibacterial and antiviral effects, silver nanoparticles (AgNP) are one of the most widely used nanomaterials worldwide in various industries, e.g., in textiles, cosmetics and biomedical-related products. Unfortunately, the lack of complete physicochemical characterization and the variety of models used to evaluate its cytotoxic/genotoxic effect make comparison and decision-making regarding their safe use difficult. In this work, we present a systematic study of the cytotoxic and genotoxic activity of the commercially available AgNPs formulation Argovit™ in <i>Allium cepa</i>. The evaluated concentration range, 5–100 µg/mL of metallic silver content (85–1666 µg/mL of complete formulation), is 10–17 times higher than the used for other previously reported polyvinylpyrrolidone (PVP)-AgNP formulations and showed no cytotoxic or genotoxic damage in <i>Allium cepa</i>. Conversely, low concentrations (5 and 10 µg/mL) promote growth without damage to roots or bulbs. Until this work, all the formulations of PVP-AgNP evaluated in <i>Allium cepa</i> regardless of their size, concentration, or the exposure time had shown phytotoxicity. The biological response observed in <i>Allium cepa</i> exposed to Argovit™ is caused by nanoparticles and not by silver ions. The metal/coating agent ratio plays a fundamental role in this response and must be considered within the key physicochemical parameters for the design and manufacture of safer nanomaterials. |
| first_indexed | 2024-03-10T18:26:23Z |
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| id | doaj.art-157044c285a543a89c5dd29c3eb2dad0 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T18:26:23Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-157044c285a543a89c5dd29c3eb2dad02023-11-20T06:56:59ZengMDPI AGNanomaterials2079-49912020-07-01107138610.3390/nano10071386Argovit™ Silver Nanoparticles Effects on <i>Allium cepa</i>: Plant Growth Promotion without Cyto Genotoxic DamageFrancisco Casillas-Figueroa0María Evarista Arellano-García1Claudia Leyva-Aguilera2Balam Ruíz-Ruíz3Roberto Luna Vázquez-Gómez4Patricia Radilla-Chávez5Rocío Alejandra Chávez-Santoscoy6Alexey Pestryakov7Yanis Toledano-Magaña8Juan Carlos García-Ramos9Nina Bogdanchikova10Escuela de Ciencias de la Salud, UABC, Blvd. Zertuche y Blvd., De los Lagos S/N Fracc, Valle Dorado, 22890 Ensenada, Baja California, MexicoFacultad de Ciencias, UABC, Carretera Transpeninsular Ensenada-Tijuana No. 3917 Col. Playitas, 22860 Ensenada, Baja California, MexicoFacultad de Ciencias, UABC, Carretera Transpeninsular Ensenada-Tijuana No. 3917 Col. Playitas, 22860 Ensenada, Baja California, MexicoFacultad de Medicina extensión los Mochis, Universidad Autónoma de Sinaloa, Av. Ángel Flores s/n, Ciudad Universitaria, 81223 Los Mochis, Sinaloa, MexicoEscuela de Ciencias de la Salud, UABC, Blvd. Zertuche y Blvd., De los Lagos S/N Fracc, Valle Dorado, 22890 Ensenada, Baja California, MexicoEscuela de Ciencias de la Salud, UABC, Blvd. Zertuche y Blvd., De los Lagos S/N Fracc, Valle Dorado, 22890 Ensenada, Baja California, MexicoCentro de Biotecnología-FEMSA, Escuela de Ingeniería y Ciencias, ITESM, Monterrey, Eugenio Garza Sada, 2501 Sur, 64849 Monterrey, Nuevo León, MexicoDepartment of Technology of Organic Substances and Polymer Materials, Tomsk Polytechnic University, 634050 Tomsk, RussiaEscuela de Ciencias de la Salud, UABC, Blvd. Zertuche y Blvd., De los Lagos S/N Fracc, Valle Dorado, 22890 Ensenada, Baja California, MexicoEscuela de Ciencias de la Salud, UABC, Blvd. Zertuche y Blvd., De los Lagos S/N Fracc, Valle Dorado, 22890 Ensenada, Baja California, MexicoCentro de Nanociencias y Nanotecnología, UNAM, Carretera Tijuana-Ensenada Km 107, 22860 Ensenada, Baja California, MexicoDue to their antibacterial and antiviral effects, silver nanoparticles (AgNP) are one of the most widely used nanomaterials worldwide in various industries, e.g., in textiles, cosmetics and biomedical-related products. Unfortunately, the lack of complete physicochemical characterization and the variety of models used to evaluate its cytotoxic/genotoxic effect make comparison and decision-making regarding their safe use difficult. In this work, we present a systematic study of the cytotoxic and genotoxic activity of the commercially available AgNPs formulation Argovit™ in <i>Allium cepa</i>. The evaluated concentration range, 5–100 µg/mL of metallic silver content (85–1666 µg/mL of complete formulation), is 10–17 times higher than the used for other previously reported polyvinylpyrrolidone (PVP)-AgNP formulations and showed no cytotoxic or genotoxic damage in <i>Allium cepa</i>. Conversely, low concentrations (5 and 10 µg/mL) promote growth without damage to roots or bulbs. Until this work, all the formulations of PVP-AgNP evaluated in <i>Allium cepa</i> regardless of their size, concentration, or the exposure time had shown phytotoxicity. The biological response observed in <i>Allium cepa</i> exposed to Argovit™ is caused by nanoparticles and not by silver ions. The metal/coating agent ratio plays a fundamental role in this response and must be considered within the key physicochemical parameters for the design and manufacture of safer nanomaterials.https://www.mdpi.com/2079-4991/10/7/1386nongenotoxic silver nanoparticlesgenotoxiccytotoxicantioxidant activitysilver ions<i>Allium cepa</i> |
| spellingShingle | Francisco Casillas-Figueroa María Evarista Arellano-García Claudia Leyva-Aguilera Balam Ruíz-Ruíz Roberto Luna Vázquez-Gómez Patricia Radilla-Chávez Rocío Alejandra Chávez-Santoscoy Alexey Pestryakov Yanis Toledano-Magaña Juan Carlos García-Ramos Nina Bogdanchikova Argovit™ Silver Nanoparticles Effects on <i>Allium cepa</i>: Plant Growth Promotion without Cyto Genotoxic Damage Nanomaterials nongenotoxic silver nanoparticles genotoxic cytotoxic antioxidant activity silver ions <i>Allium cepa</i> |
| title | Argovit™ Silver Nanoparticles Effects on <i>Allium cepa</i>: Plant Growth Promotion without Cyto Genotoxic Damage |
| title_full | Argovit™ Silver Nanoparticles Effects on <i>Allium cepa</i>: Plant Growth Promotion without Cyto Genotoxic Damage |
| title_fullStr | Argovit™ Silver Nanoparticles Effects on <i>Allium cepa</i>: Plant Growth Promotion without Cyto Genotoxic Damage |
| title_full_unstemmed | Argovit™ Silver Nanoparticles Effects on <i>Allium cepa</i>: Plant Growth Promotion without Cyto Genotoxic Damage |
| title_short | Argovit™ Silver Nanoparticles Effects on <i>Allium cepa</i>: Plant Growth Promotion without Cyto Genotoxic Damage |
| title_sort | argovit™ silver nanoparticles effects on i allium cepa i plant growth promotion without cyto genotoxic damage |
| topic | nongenotoxic silver nanoparticles genotoxic cytotoxic antioxidant activity silver ions <i>Allium cepa</i> |
| url | https://www.mdpi.com/2079-4991/10/7/1386 |
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