Associations of bullying perpetration and peer victimization subtypes with preadolescent’s suicidality, non-suicidal self-injury, neurocognition, and brain development
Abstract Background Although both peer victimization and bullying perpetration negatively impact preadolescents’ development, the underlying neurobiological mechanism of this adverse relationship remains unclear. Besides, the specific psycho-cognitive patterns of different bullying subtypes also nee...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-04-01
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| Series: | BMC Medicine |
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| Online Access: | https://doi.org/10.1186/s12916-023-02808-8 |
| _version_ | 1827966232880480256 |
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| author | Xue Wen Yinuo Shu Diyang Qu Yinzhe Wang Zaixu Cui Xiaoqian Zhang Runsen Chen |
| author_facet | Xue Wen Yinuo Shu Diyang Qu Yinzhe Wang Zaixu Cui Xiaoqian Zhang Runsen Chen |
| author_sort | Xue Wen |
| collection | DOAJ |
| description | Abstract Background Although both peer victimization and bullying perpetration negatively impact preadolescents’ development, the underlying neurobiological mechanism of this adverse relationship remains unclear. Besides, the specific psycho-cognitive patterns of different bullying subtypes also need further exploration, warranting large-scale studies on both general bullying and specific bullying subtypes. Methods We adopted a retrospective methodology by utilizing the data from the Adolescent Brain and Cognitive DevelopmentSM Study (ABCD Study®) cohort collected between July 2018 and January 2021. Participants were preadolescents aged from 10 to 13 years. The main purpose of our study is to examine the associations of general and specific peer victimization/bullying perpetration with preadolescents’ (1) suicidality and non-suicidal self-injury; (2) executive function and memory, including attention inhibition, processing speed, emotion working memory, and episodic memory; (3) brain structure abnormalities; and (4) brain network disturbances. Age, sex, race/ethnicity, body mass index (BMI), socioeconomic status (SES), and data acquisition site were included as covariates. Results A total of 5819 participants aged from 10 to 13 years were included in this study. Higher risks of suicide ideation, suicide attempt, and non-suicidal self-injury were found to be associated with both bullying perpetration/peer victimization and their subtypes (i.e., overt, relational, and reputational). Meanwhile, poor episodic memory was shown to be associated with general victimization. As for perpetration, across all four tasks, significant positive associations of relational perpetration with executive function and episodic memory consistently manifested, yet opposite patterns were shown in overt perpetration. Notably, distinct psycho-cognitive patterns were shown among different subtypes. Additionally, victimization was associated with structural brain abnormalities in the bilateral paracentral and posterior cingulate cortex. Furthermore, victimization was associated with brain network disturbances between default mode network and dorsal attention network, between default mode network and fronto-parietal network, and ventral attention network related connectivities, including default mode network, dorsal attention network, cingulo-opercular network, cingulo-parietal network, and sensorimotor hand network. Perpetration was also associated with brain network disturbances between the attention network and the sensorimotor hand network. Conclusions Our findings offered new evidence for the literature landscape by emphasizing the associations of bullying experiences with preadolescents’ clinical characteristics and cognitive functions, while distinctive psycho-cognitive patterns were shown among different subtypes. Additionally, there is evidence that these associations are related to neurocognitive brain networks involved in attention control and episodic retrieval. Given our findings, future interventions targeting ameliorating the deleterious effect of bullying experiences on preadolescents should consider their subtypes and utilize an ecosystemic approach involving all responsible parties. |
| first_indexed | 2024-04-09T17:46:46Z |
| format | Article |
| id | doaj.art-1570adb874a44863b662a61c698b2888 |
| institution | Directory Open Access Journal |
| issn | 1741-7015 |
| language | English |
| last_indexed | 2024-04-09T17:46:46Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medicine |
| spelling | doaj.art-1570adb874a44863b662a61c698b28882023-04-16T11:16:35ZengBMCBMC Medicine1741-70152023-04-0121111210.1186/s12916-023-02808-8Associations of bullying perpetration and peer victimization subtypes with preadolescent’s suicidality, non-suicidal self-injury, neurocognition, and brain developmentXue Wen0Yinuo Shu1Diyang Qu2Yinzhe Wang3Zaixu Cui4Xiaoqian Zhang5Runsen Chen6Vanke School of Public Health, Tsinghua UniversityChinese Institute for Brain ResearchVanke School of Public Health, Tsinghua UniversityVanke School of Public Health, Tsinghua UniversityChinese Institute for Brain ResearchDepartment of Psychiatry, Tsinghua University Yuquan HospitalVanke School of Public Health, Tsinghua UniversityAbstract Background Although both peer victimization and bullying perpetration negatively impact preadolescents’ development, the underlying neurobiological mechanism of this adverse relationship remains unclear. Besides, the specific psycho-cognitive patterns of different bullying subtypes also need further exploration, warranting large-scale studies on both general bullying and specific bullying subtypes. Methods We adopted a retrospective methodology by utilizing the data from the Adolescent Brain and Cognitive DevelopmentSM Study (ABCD Study®) cohort collected between July 2018 and January 2021. Participants were preadolescents aged from 10 to 13 years. The main purpose of our study is to examine the associations of general and specific peer victimization/bullying perpetration with preadolescents’ (1) suicidality and non-suicidal self-injury; (2) executive function and memory, including attention inhibition, processing speed, emotion working memory, and episodic memory; (3) brain structure abnormalities; and (4) brain network disturbances. Age, sex, race/ethnicity, body mass index (BMI), socioeconomic status (SES), and data acquisition site were included as covariates. Results A total of 5819 participants aged from 10 to 13 years were included in this study. Higher risks of suicide ideation, suicide attempt, and non-suicidal self-injury were found to be associated with both bullying perpetration/peer victimization and their subtypes (i.e., overt, relational, and reputational). Meanwhile, poor episodic memory was shown to be associated with general victimization. As for perpetration, across all four tasks, significant positive associations of relational perpetration with executive function and episodic memory consistently manifested, yet opposite patterns were shown in overt perpetration. Notably, distinct psycho-cognitive patterns were shown among different subtypes. Additionally, victimization was associated with structural brain abnormalities in the bilateral paracentral and posterior cingulate cortex. Furthermore, victimization was associated with brain network disturbances between default mode network and dorsal attention network, between default mode network and fronto-parietal network, and ventral attention network related connectivities, including default mode network, dorsal attention network, cingulo-opercular network, cingulo-parietal network, and sensorimotor hand network. Perpetration was also associated with brain network disturbances between the attention network and the sensorimotor hand network. Conclusions Our findings offered new evidence for the literature landscape by emphasizing the associations of bullying experiences with preadolescents’ clinical characteristics and cognitive functions, while distinctive psycho-cognitive patterns were shown among different subtypes. Additionally, there is evidence that these associations are related to neurocognitive brain networks involved in attention control and episodic retrieval. Given our findings, future interventions targeting ameliorating the deleterious effect of bullying experiences on preadolescents should consider their subtypes and utilize an ecosystemic approach involving all responsible parties.https://doi.org/10.1186/s12916-023-02808-8BullyingSubtypeBrain networkSuicideNSSI |
| spellingShingle | Xue Wen Yinuo Shu Diyang Qu Yinzhe Wang Zaixu Cui Xiaoqian Zhang Runsen Chen Associations of bullying perpetration and peer victimization subtypes with preadolescent’s suicidality, non-suicidal self-injury, neurocognition, and brain development BMC Medicine Bullying Subtype Brain network Suicide NSSI |
| title | Associations of bullying perpetration and peer victimization subtypes with preadolescent’s suicidality, non-suicidal self-injury, neurocognition, and brain development |
| title_full | Associations of bullying perpetration and peer victimization subtypes with preadolescent’s suicidality, non-suicidal self-injury, neurocognition, and brain development |
| title_fullStr | Associations of bullying perpetration and peer victimization subtypes with preadolescent’s suicidality, non-suicidal self-injury, neurocognition, and brain development |
| title_full_unstemmed | Associations of bullying perpetration and peer victimization subtypes with preadolescent’s suicidality, non-suicidal self-injury, neurocognition, and brain development |
| title_short | Associations of bullying perpetration and peer victimization subtypes with preadolescent’s suicidality, non-suicidal self-injury, neurocognition, and brain development |
| title_sort | associations of bullying perpetration and peer victimization subtypes with preadolescent s suicidality non suicidal self injury neurocognition and brain development |
| topic | Bullying Subtype Brain network Suicide NSSI |
| url | https://doi.org/10.1186/s12916-023-02808-8 |
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