Pineal Gland Tumors: A Review
The pineal gland is a small, pinecone-shaped endocrine gland that participates in the biological rhythm regulation of vertebrates. The recognized major product of the pineal gland is melatonin—a multifunctional endogenous indoleamine. Accumulating evidence suggests that the pineal gland is important...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/13/7/1547 |
| _version_ | 1797539797670035456 |
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| author | Gaia Favero Francesca Bonomini Rita Rezzani |
| author_facet | Gaia Favero Francesca Bonomini Rita Rezzani |
| author_sort | Gaia Favero |
| collection | DOAJ |
| description | The pineal gland is a small, pinecone-shaped endocrine gland that participates in the biological rhythm regulation of vertebrates. The recognized major product of the pineal gland is melatonin—a multifunctional endogenous indoleamine. Accumulating evidence suggests that the pineal gland is important for preserving ideal health conditions in vertebrate. Tumors of the pineal region account for approximately 3–11% of pediatric brain neoplasms but fewer than 1% of brain neoplasms in adults. It is fundamental to expand advanced imaging techniques together with both clinical and laboratory knowledge, to help to differentiate among pineal neoplasms and thus facilitate accurate primary diagnoses and proper therapeutic interventions. In this review, we report the gross anatomy of the pineal gland and its functional significance and discuss the clinical relevance of pineal gland tumors, underlining the importance of identifying the leading causes of pineal region masses. |
| first_indexed | 2024-03-10T12:50:58Z |
| format | Article |
| id | doaj.art-15759414de354ca293470773b7c2bc80 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T12:50:58Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-15759414de354ca293470773b7c2bc802023-11-21T13:03:43ZengMDPI AGCancers2072-66942021-03-01137154710.3390/cancers13071547Pineal Gland Tumors: A ReviewGaia Favero0Francesca Bonomini1Rita Rezzani2Anatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, ItalyAnatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, ItalyAnatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, ItalyThe pineal gland is a small, pinecone-shaped endocrine gland that participates in the biological rhythm regulation of vertebrates. The recognized major product of the pineal gland is melatonin—a multifunctional endogenous indoleamine. Accumulating evidence suggests that the pineal gland is important for preserving ideal health conditions in vertebrate. Tumors of the pineal region account for approximately 3–11% of pediatric brain neoplasms but fewer than 1% of brain neoplasms in adults. It is fundamental to expand advanced imaging techniques together with both clinical and laboratory knowledge, to help to differentiate among pineal neoplasms and thus facilitate accurate primary diagnoses and proper therapeutic interventions. In this review, we report the gross anatomy of the pineal gland and its functional significance and discuss the clinical relevance of pineal gland tumors, underlining the importance of identifying the leading causes of pineal region masses.https://www.mdpi.com/2072-6694/13/7/1547pineal glandbrain neoplasmspineal germ cell tumorspineal parenchymal tumorpineal metastasis |
| spellingShingle | Gaia Favero Francesca Bonomini Rita Rezzani Pineal Gland Tumors: A Review Cancers pineal gland brain neoplasms pineal germ cell tumors pineal parenchymal tumor pineal metastasis |
| title | Pineal Gland Tumors: A Review |
| title_full | Pineal Gland Tumors: A Review |
| title_fullStr | Pineal Gland Tumors: A Review |
| title_full_unstemmed | Pineal Gland Tumors: A Review |
| title_short | Pineal Gland Tumors: A Review |
| title_sort | pineal gland tumors a review |
| topic | pineal gland brain neoplasms pineal germ cell tumors pineal parenchymal tumor pineal metastasis |
| url | https://www.mdpi.com/2072-6694/13/7/1547 |
| work_keys_str_mv | AT gaiafavero pinealglandtumorsareview AT francescabonomini pinealglandtumorsareview AT ritarezzani pinealglandtumorsareview |