Oncogenic Signalling of PEAK2 Pseudokinase in Colon Cancer

Oncogenic Signalling of PEAK2 Pseudokinase in Colon Cancer

The PEAK family pseudokinases are essential components of tyrosine kinase (TK) pathways that regulate cell growth and adhesion; however, their role in human cancer remains unclear. Here, we report an oncogenic activity of the pseudokinase PEAK2 in colorectal cancer (CRC). Notably, high <i>PRAG...

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Bibliographic Details
Main Authors: Céline Lecointre, Elise Fourgous, Ingrid Montarras, Clément Kerneur, Valérie Simon, Yvan Boublik, Débora Bonenfant, Bruno Robert, Pierre Martineau, Serge Roche
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
pseudokinase
oncogene
cell signalling
cell migration
actin cytoskeleton
colorectal cancer
Online Access:https://www.mdpi.com/2072-6694/14/12/2981

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