Influence of dietary protein on serum phosphorous levels in peritoneal dialysis patients with different initial transport function
Introduction This cross-sectional study investigated the influence of dietary protein intake (DPI) on serum phosphate levels in peritoneal dialysis (PD) patients and determined the DPI cutoff required to prevent hyperphosphatemia.Methods A total of 504 PD patients were categorized into fast (4 h dia...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | Renal Failure |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2022.2148537 |
| _version_ | 1797987104888717312 |
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| author | Xiao-Pei Wang Ying Ma Jing Lv Yu Liang Li Jin Wan-Hong Lu Chang-Na Liang Bao Qian Zhao Li |
| author_facet | Xiao-Pei Wang Ying Ma Jing Lv Yu Liang Li Jin Wan-Hong Lu Chang-Na Liang Bao Qian Zhao Li |
| author_sort | Xiao-Pei Wang |
| collection | DOAJ |
| description | Introduction This cross-sectional study investigated the influence of dietary protein intake (DPI) on serum phosphate levels in peritoneal dialysis (PD) patients and determined the DPI cutoff required to prevent hyperphosphatemia.Methods A total of 504 PD patients were categorized into fast (4 h dialysate/plasma [D/P] creatinine clearance ≥0.65) or slow (<0.65) peritoneal transporters. Serum phosphorus and peritoneal solute clearance were compared between the groups with different DPI.Results The fast peritoneal transporters (n = 233) were older, had lower serum albumin and phosphorus levels, and had higher peritoneal phosphorus clearance (all p < 0.001). Among the slow transporters (n = 271), serum phosphorus levels were significantly higher among patients with DPI > 1.0 g/kg/d (p < 0.001). High DPI only increased the hyperphosphatemia risk in slow transporters (not in high transporters). DPI ≥1.026 g increased the hyperphosphatemia risk in those patients (area under the curve: 0.66, p = 0.001).Conclusion High DPI increases the hyperphosphatemia risk in PD patients with slower peritoneal transport function. |
| first_indexed | 2024-04-11T07:43:35Z |
| format | Article |
| id | doaj.art-157cc3f3d0644c54b5880f8b5aca9dcc |
| institution | Directory Open Access Journal |
| issn | 0886-022X 1525-6049 |
| language | English |
| last_indexed | 2024-04-11T07:43:35Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Renal Failure |
| spelling | doaj.art-157cc3f3d0644c54b5880f8b5aca9dcc2022-12-22T04:36:23ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492022-12-014412085209210.1080/0886022X.2022.2148537Influence of dietary protein on serum phosphorous levels in peritoneal dialysis patients with different initial transport functionXiao-Pei Wang0Ying Ma1Jing Lv2Yu Liang3Li Jin4Wan-Hong Lu5Chang-Na Liang6Bao Qian7Zhao Li8Department of Nephrology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Nephrology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Nephrology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Nephrology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Nephrology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Nephrology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Nephrology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Nephrology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaDepartment of Nephrology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaIntroduction This cross-sectional study investigated the influence of dietary protein intake (DPI) on serum phosphate levels in peritoneal dialysis (PD) patients and determined the DPI cutoff required to prevent hyperphosphatemia.Methods A total of 504 PD patients were categorized into fast (4 h dialysate/plasma [D/P] creatinine clearance ≥0.65) or slow (<0.65) peritoneal transporters. Serum phosphorus and peritoneal solute clearance were compared between the groups with different DPI.Results The fast peritoneal transporters (n = 233) were older, had lower serum albumin and phosphorus levels, and had higher peritoneal phosphorus clearance (all p < 0.001). Among the slow transporters (n = 271), serum phosphorus levels were significantly higher among patients with DPI > 1.0 g/kg/d (p < 0.001). High DPI only increased the hyperphosphatemia risk in slow transporters (not in high transporters). DPI ≥1.026 g increased the hyperphosphatemia risk in those patients (area under the curve: 0.66, p = 0.001).Conclusion High DPI increases the hyperphosphatemia risk in PD patients with slower peritoneal transport function.https://www.tandfonline.com/doi/10.1080/0886022X.2022.2148537Dietary protein intakehyperphosphatemiaperitoneal dialysisperitoneal transport functionperitoneal phosphate clearance |
| spellingShingle | Xiao-Pei Wang Ying Ma Jing Lv Yu Liang Li Jin Wan-Hong Lu Chang-Na Liang Bao Qian Zhao Li Influence of dietary protein on serum phosphorous levels in peritoneal dialysis patients with different initial transport function Renal Failure Dietary protein intake hyperphosphatemia peritoneal dialysis peritoneal transport function peritoneal phosphate clearance |
| title | Influence of dietary protein on serum phosphorous levels in peritoneal dialysis patients with different initial transport function |
| title_full | Influence of dietary protein on serum phosphorous levels in peritoneal dialysis patients with different initial transport function |
| title_fullStr | Influence of dietary protein on serum phosphorous levels in peritoneal dialysis patients with different initial transport function |
| title_full_unstemmed | Influence of dietary protein on serum phosphorous levels in peritoneal dialysis patients with different initial transport function |
| title_short | Influence of dietary protein on serum phosphorous levels in peritoneal dialysis patients with different initial transport function |
| title_sort | influence of dietary protein on serum phosphorous levels in peritoneal dialysis patients with different initial transport function |
| topic | Dietary protein intake hyperphosphatemia peritoneal dialysis peritoneal transport function peritoneal phosphate clearance |
| url | https://www.tandfonline.com/doi/10.1080/0886022X.2022.2148537 |
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