Interplay among positive and negative symptoms, neurocognition, social cognition, and functioning in clinically stable patients with schizophrenia: a network analysis [version 3; peer review: 2 approved]
Background: Schizophrenia has a broad range of interrelated symptoms and impairment in functioning. The objective of the study was to explore the interplay between positive symptoms, negative symptoms, neurocognition, social cognition and real-life functioning in patients with schizophrenia using ne...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2022-04-01
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| Series: | F1000Research |
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| Online Access: | https://f1000research.com/articles/10-1258/v3 |
| _version_ | 1818212981620604928 |
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| author | Thammanard Charernboon |
| author_facet | Thammanard Charernboon |
| author_sort | Thammanard Charernboon |
| collection | DOAJ |
| description | Background: Schizophrenia has a broad range of interrelated symptoms and impairment in functioning. The objective of the study was to explore the interplay between positive symptoms, negative symptoms, neurocognition, social cognition and real-life functioning in patients with schizophrenia using network analysis. Methods: Participants were 64 clinically stable patients with schizophrenia. Psychopathologic, neurocognition, social cognition, and functioning were measured using the Scale for the Assessment of Positive Symptoms, Scale for the Assessment of Negative Symptoms, Addenbrooke’s Cognitive Examination III, Faces test, Reading the Mind in the Eyes test, and Personal Social Performance scale. Results: The network analysis suggested that functioning was the most central in the network followed by avolition and asociality. Functioning was directly connected to avolition, asociality, blunted affect, neurocognition and emotion recognition. The positive symptoms were the most remote and therefore the least important node. Conclusion: The high centrality of functioning suggests the need for improving of everyday life skills for patients with schizophrenia. Moreover, treatment of specific negative symptoms, neurocognition and emotion recognition could also enhance functional outcome. |
| first_indexed | 2024-12-12T05:57:02Z |
| format | Article |
| id | doaj.art-157dfe2b060b46dd9ef4f85a4082e280 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-12-12T05:57:02Z |
| publishDate | 2022-04-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-157dfe2b060b46dd9ef4f85a4082e2802022-12-22T00:35:32ZengF1000 Research LtdF1000Research2046-14022022-04-0110125399Interplay among positive and negative symptoms, neurocognition, social cognition, and functioning in clinically stable patients with schizophrenia: a network analysis [version 3; peer review: 2 approved]Thammanard Charernboon0https://orcid.org/0000-0002-3783-6691Faculty of Medicine, Thammasat University, Pathumthani, 12120, ThailandBackground: Schizophrenia has a broad range of interrelated symptoms and impairment in functioning. The objective of the study was to explore the interplay between positive symptoms, negative symptoms, neurocognition, social cognition and real-life functioning in patients with schizophrenia using network analysis. Methods: Participants were 64 clinically stable patients with schizophrenia. Psychopathologic, neurocognition, social cognition, and functioning were measured using the Scale for the Assessment of Positive Symptoms, Scale for the Assessment of Negative Symptoms, Addenbrooke’s Cognitive Examination III, Faces test, Reading the Mind in the Eyes test, and Personal Social Performance scale. Results: The network analysis suggested that functioning was the most central in the network followed by avolition and asociality. Functioning was directly connected to avolition, asociality, blunted affect, neurocognition and emotion recognition. The positive symptoms were the most remote and therefore the least important node. Conclusion: The high centrality of functioning suggests the need for improving of everyday life skills for patients with schizophrenia. Moreover, treatment of specific negative symptoms, neurocognition and emotion recognition could also enhance functional outcome.https://f1000research.com/articles/10-1258/v3Negative symptoms network analysis neurocognition schizophrenia social cognitioneng |
| spellingShingle | Thammanard Charernboon Interplay among positive and negative symptoms, neurocognition, social cognition, and functioning in clinically stable patients with schizophrenia: a network analysis [version 3; peer review: 2 approved] F1000Research Negative symptoms network analysis neurocognition schizophrenia social cognition eng |
| title | Interplay among positive and negative symptoms, neurocognition, social cognition, and functioning in clinically stable patients with schizophrenia: a network analysis [version 3; peer review: 2 approved] |
| title_full | Interplay among positive and negative symptoms, neurocognition, social cognition, and functioning in clinically stable patients with schizophrenia: a network analysis [version 3; peer review: 2 approved] |
| title_fullStr | Interplay among positive and negative symptoms, neurocognition, social cognition, and functioning in clinically stable patients with schizophrenia: a network analysis [version 3; peer review: 2 approved] |
| title_full_unstemmed | Interplay among positive and negative symptoms, neurocognition, social cognition, and functioning in clinically stable patients with schizophrenia: a network analysis [version 3; peer review: 2 approved] |
| title_short | Interplay among positive and negative symptoms, neurocognition, social cognition, and functioning in clinically stable patients with schizophrenia: a network analysis [version 3; peer review: 2 approved] |
| title_sort | interplay among positive and negative symptoms neurocognition social cognition and functioning in clinically stable patients with schizophrenia a network analysis version 3 peer review 2 approved |
| topic | Negative symptoms network analysis neurocognition schizophrenia social cognition eng |
| url | https://f1000research.com/articles/10-1258/v3 |
| work_keys_str_mv | AT thammanardcharernboon interplayamongpositiveandnegativesymptomsneurocognitionsocialcognitionandfunctioninginclinicallystablepatientswithschizophreniaanetworkanalysisversion3peerreview2approved |