Metabolic Syndrome and Nonalcoholic Fatty Liver Disease: Nutritional Approach for Prevention
Background: Metabolic syndrome is a cluster of metabolic risk factors that come together in a single individual. These metabolic factors include insulin resistance, hypertension (high blood pressure), dyslipidemia, and an increased risk for clotting. Patients are most often overweight or obese. The...
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| Format: | Article |
| Language: | fas |
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Isfahan University of Medical Sciences
2013-11-01
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| Series: | مجله دانشکده پزشکی اصفهان |
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| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/2611 |
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| author | Zamzam Paknahad Hadi Zeraei-Bidgoli |
| author_facet | Zamzam Paknahad Hadi Zeraei-Bidgoli |
| author_sort | Zamzam Paknahad |
| collection | DOAJ |
| description | Background: Metabolic syndrome is a cluster of metabolic risk factors that come together in a single individual. These metabolic factors include insulin resistance, hypertension (high blood pressure), dyslipidemia, and an increased risk for clotting. Patients are most often overweight or obese. The development of nonalcoholic fatty liver disease (NAFLD) is strongly associated with the metabolic syndrome as reflected by the fact that most of the patients with NAFLD have more than one feature of metabolic syndrome. The aim of this review was to summarize the current knowledge on the epidemiology and pathophysiology of both NAFLD and metabolic syndrome and the findings about the effects nutrient content or specific food components (such as ω3 fatty acids).
Methods: We searched Pubmed, ISI web of science, and EMBASE databases by using “Metabolic syndrome’, ‘Nonalcoholic fatty liver” , “Metabolic syndrome & diet”, “Metabolic syndrome & nonalcoholic fatty liver”, ‘Nonalcoholic fatty liver & diet” , “Nonalcoholic fatty liver & nutrition”, and “Metabolic syndrome & nutrition” from 2008 until 2013.
Findings: The global increase in the prevalence of obesity is associated with NAFLD. NAFLD is also commonly associated with an increased risk of Type 2 diabetes mellitus development. Although there are no ideal options available for NAFLD treatment, dietary modification has a major role. Dietary patterns highly in fruit and vegetable content were generally found to be associated with lower prevalence of metabolic syndrome. High meat intake was associated with components of metabolic syndrome, especially impaired glucose tolerance. Intake of trans fatty acids from hydrogenated oils found to increase inflammatory markers. A low carbohydrate and saturated fat and high fiber and ω3 fatty acid diet is likely to be beneficial. The higher intake of soft drinks is associated with an increased risk of NAFLD. It is recommended to limit the intake of high-fructose foods and beverages in the NAFLD population. Findings showed negative correlation between coffee consumption and metabolic syndrome, because of the lower prevalence of hypertriglyceridemia, and data suggested coffee intake can reduce the risk of NAFLD.
Conclusion: A gradual weight reduction and physical activity program is still the gold standard of NAFLD treatment. Regular consumption of fruit and vegetables is recommended to reduce the risk of developing metabolic syndrome. |
| first_indexed | 2024-03-12T08:34:32Z |
| format | Article |
| id | doaj.art-157e70080ebd45d79a7edbb1b1903f79 |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T08:34:32Z |
| publishDate | 2013-11-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-157e70080ebd45d79a7edbb1b1903f792023-09-02T17:18:08ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2013-11-0131252146114801420Metabolic Syndrome and Nonalcoholic Fatty Liver Disease: Nutritional Approach for PreventionZamzam Paknahad0Hadi Zeraei-Bidgoli1Associate Professor, Department of Clinical Nutrition, School of Nutrition, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Nutrition School of Nutrition, Isfahan University of Medical Sciences, Isfahan, IranBackground: Metabolic syndrome is a cluster of metabolic risk factors that come together in a single individual. These metabolic factors include insulin resistance, hypertension (high blood pressure), dyslipidemia, and an increased risk for clotting. Patients are most often overweight or obese. The development of nonalcoholic fatty liver disease (NAFLD) is strongly associated with the metabolic syndrome as reflected by the fact that most of the patients with NAFLD have more than one feature of metabolic syndrome. The aim of this review was to summarize the current knowledge on the epidemiology and pathophysiology of both NAFLD and metabolic syndrome and the findings about the effects nutrient content or specific food components (such as ω3 fatty acids). Methods: We searched Pubmed, ISI web of science, and EMBASE databases by using “Metabolic syndrome’, ‘Nonalcoholic fatty liver” , “Metabolic syndrome & diet”, “Metabolic syndrome & nonalcoholic fatty liver”, ‘Nonalcoholic fatty liver & diet” , “Nonalcoholic fatty liver & nutrition”, and “Metabolic syndrome & nutrition” from 2008 until 2013. Findings: The global increase in the prevalence of obesity is associated with NAFLD. NAFLD is also commonly associated with an increased risk of Type 2 diabetes mellitus development. Although there are no ideal options available for NAFLD treatment, dietary modification has a major role. Dietary patterns highly in fruit and vegetable content were generally found to be associated with lower prevalence of metabolic syndrome. High meat intake was associated with components of metabolic syndrome, especially impaired glucose tolerance. Intake of trans fatty acids from hydrogenated oils found to increase inflammatory markers. A low carbohydrate and saturated fat and high fiber and ω3 fatty acid diet is likely to be beneficial. The higher intake of soft drinks is associated with an increased risk of NAFLD. It is recommended to limit the intake of high-fructose foods and beverages in the NAFLD population. Findings showed negative correlation between coffee consumption and metabolic syndrome, because of the lower prevalence of hypertriglyceridemia, and data suggested coffee intake can reduce the risk of NAFLD. Conclusion: A gradual weight reduction and physical activity program is still the gold standard of NAFLD treatment. Regular consumption of fruit and vegetables is recommended to reduce the risk of developing metabolic syndrome.http://jims.mui.ac.ir/index.php/jims/article/view/2611Metabolic syndromeNonalcoholic fatty liver disease (NAFLD)DietNutrition |
| spellingShingle | Zamzam Paknahad Hadi Zeraei-Bidgoli Metabolic Syndrome and Nonalcoholic Fatty Liver Disease: Nutritional Approach for Prevention مجله دانشکده پزشکی اصفهان Metabolic syndrome Nonalcoholic fatty liver disease (NAFLD) Diet Nutrition |
| title | Metabolic Syndrome and Nonalcoholic Fatty Liver Disease: Nutritional Approach for Prevention |
| title_full | Metabolic Syndrome and Nonalcoholic Fatty Liver Disease: Nutritional Approach for Prevention |
| title_fullStr | Metabolic Syndrome and Nonalcoholic Fatty Liver Disease: Nutritional Approach for Prevention |
| title_full_unstemmed | Metabolic Syndrome and Nonalcoholic Fatty Liver Disease: Nutritional Approach for Prevention |
| title_short | Metabolic Syndrome and Nonalcoholic Fatty Liver Disease: Nutritional Approach for Prevention |
| title_sort | metabolic syndrome and nonalcoholic fatty liver disease nutritional approach for prevention |
| topic | Metabolic syndrome Nonalcoholic fatty liver disease (NAFLD) Diet Nutrition |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/2611 |
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