A review on genus Millettia: Traditional uses, phytochemicals and pharmacological activities
The genus Millettia belongs to Fabaceae includes 200 species which are distributed in tropical and subtropical regions of the world. Plants belong to this genus are used as folkloric medicine, for the treatment of different ailments like in wound healing, boil, sores, skin diseases, snake bite, musc...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-12-01
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| Series: | Saudi Pharmaceutical Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319016420302504 |
| _version_ | 1818449878608510976 |
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| author | Rasmita Jena Diptirani Rath Sudhanshu Sekhar Rout Durga Madhab Kar |
| author_facet | Rasmita Jena Diptirani Rath Sudhanshu Sekhar Rout Durga Madhab Kar |
| author_sort | Rasmita Jena |
| collection | DOAJ |
| description | The genus Millettia belongs to Fabaceae includes 200 species which are distributed in tropical and subtropical regions of the world. Plants belong to this genus are used as folkloric medicine, for the treatment of different ailments like in wound healing, boil, sores, skin diseases, snake bite, muscle aches, pains, rheumatic arthritis, and gynaecological diseases. The aim of the review is to provide updated, comprehensive and categorized information on the aspects of ethnobotanical, phytochemical, pharmacological uses and toxicity of genus Millettia in order to identify their therapeutic potential and generate space for future research opportunities. The present study comprises of isolated flavonoids, phenolic compounds, phytosterols, saponins, alkaloids, polysaccharides, terpenoids and resins and pharmacological activities of various Millettia species. The relevant data were searched by using the keyword “Millettia” in different scientific databases like, “Google Scholar”; “NISCAIR repository”; “Pub Med”; “Science Direct”; “Scopus” and the taxonomy is validated by “The Plant List”. This review discusses the existing information of the traditional evaluation as well as phytochemical and pharmacological evaluation of the extract and active constituents of the genus “Millettia”. This review confirms that several Millettia species have emerged as a high-quality medicine in a traditional system for arthritis, wound healing, inflammation, skin diseases. Numerous conventional uses of Millettia species have been validated by modern pharmacology research. Intensive investigations of the genus Millettia relating to phytochemistry and pharmacology, especially their mechanism of action, safety, and efficacy could be the future research interests by the researcher in the area of phytomedicine. |
| first_indexed | 2024-12-14T20:42:24Z |
| format | Article |
| id | doaj.art-1582adabc8d4418cbd1144b9ac243818 |
| institution | Directory Open Access Journal |
| issn | 1319-0164 |
| language | English |
| last_indexed | 2024-12-14T20:42:24Z |
| publishDate | 2020-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Saudi Pharmaceutical Journal |
| spelling | doaj.art-1582adabc8d4418cbd1144b9ac2438182022-12-21T22:48:13ZengElsevierSaudi Pharmaceutical Journal1319-01642020-12-01281216861703A review on genus Millettia: Traditional uses, phytochemicals and pharmacological activitiesRasmita Jena0Diptirani Rath1Sudhanshu Sekhar Rout2Durga Madhab Kar3Department of Pharmacology, School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan Deemed to be University, Bhubaneswar 751003, IndiaDepartment of Pharmacology, School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan Deemed to be University, Bhubaneswar 751003, IndiaDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan Deemed to be University, Bhubaneswar 751003, IndiaDepartment of Pharmacology, School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan Deemed to be University, Bhubaneswar 751003, India; Corresponding author at: Department of Pharmacology, School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan Deemed to be University, Bhubaneswar 751003, India.The genus Millettia belongs to Fabaceae includes 200 species which are distributed in tropical and subtropical regions of the world. Plants belong to this genus are used as folkloric medicine, for the treatment of different ailments like in wound healing, boil, sores, skin diseases, snake bite, muscle aches, pains, rheumatic arthritis, and gynaecological diseases. The aim of the review is to provide updated, comprehensive and categorized information on the aspects of ethnobotanical, phytochemical, pharmacological uses and toxicity of genus Millettia in order to identify their therapeutic potential and generate space for future research opportunities. The present study comprises of isolated flavonoids, phenolic compounds, phytosterols, saponins, alkaloids, polysaccharides, terpenoids and resins and pharmacological activities of various Millettia species. The relevant data were searched by using the keyword “Millettia” in different scientific databases like, “Google Scholar”; “NISCAIR repository”; “Pub Med”; “Science Direct”; “Scopus” and the taxonomy is validated by “The Plant List”. This review discusses the existing information of the traditional evaluation as well as phytochemical and pharmacological evaluation of the extract and active constituents of the genus “Millettia”. This review confirms that several Millettia species have emerged as a high-quality medicine in a traditional system for arthritis, wound healing, inflammation, skin diseases. Numerous conventional uses of Millettia species have been validated by modern pharmacology research. Intensive investigations of the genus Millettia relating to phytochemistry and pharmacology, especially their mechanism of action, safety, and efficacy could be the future research interests by the researcher in the area of phytomedicine.http://www.sciencedirect.com/science/article/pii/S1319016420302504MillettiaFabaceaeEthnomedicineBiological activitiesChemical constituents |
| spellingShingle | Rasmita Jena Diptirani Rath Sudhanshu Sekhar Rout Durga Madhab Kar A review on genus Millettia: Traditional uses, phytochemicals and pharmacological activities Saudi Pharmaceutical Journal Millettia Fabaceae Ethnomedicine Biological activities Chemical constituents |
| title | A review on genus Millettia: Traditional uses, phytochemicals and pharmacological activities |
| title_full | A review on genus Millettia: Traditional uses, phytochemicals and pharmacological activities |
| title_fullStr | A review on genus Millettia: Traditional uses, phytochemicals and pharmacological activities |
| title_full_unstemmed | A review on genus Millettia: Traditional uses, phytochemicals and pharmacological activities |
| title_short | A review on genus Millettia: Traditional uses, phytochemicals and pharmacological activities |
| title_sort | review on genus millettia traditional uses phytochemicals and pharmacological activities |
| topic | Millettia Fabaceae Ethnomedicine Biological activities Chemical constituents |
| url | http://www.sciencedirect.com/science/article/pii/S1319016420302504 |
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