BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-κB and Activating PKA/CREB

BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-κB and Activating PKA/CREB

Microglia-mediated neuroinflammatory responses are inevitable and important pathological processes in several kinds of disorder of the central nervous system (CNS). Therefore, alleviating activated microglia-induced inflammatory process might be a valuable therapeutic approach to neuroinflammation-r...

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Bibliographic Details
Main Authors: Chuwen Li, Tongkai Chen, Hefeng Zhou, Yu Feng, Maggie P. M. Hoi, Dan Ma, Chao Zhao, Ying Zheng, Simon M. Y. Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
BHDPC
neuroinflammation
microglia
NF-κB
CREB
PKA
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00614/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00614/full

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