Epidemiology and Clinical Characteristics of Rotavirus and Norovirus Infections in Hospitalized Children Less Than 5 Yaers of Age With Acute Gastroenteritis in Tehran, Iran
Acute gastroenteritis is one of the most important causes of death in children in developing countries which cause by different enteropathogens, including bacteria, viruses, and parasites. Among these, most of the acute gastroenteritis in children are caused by viral infections mainly by rotavirus a...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2020-05-01
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| Series: | Acta Medica Iranica |
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| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/7721 |
| _version_ | 1818489923524624384 |
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| author | Arash Arashkia Behrooz Nejati Mahsa Farsi Somayeh Jalilvand Alireza Nateghian Aliakbar Rahbarimanesh Fereshteh Moshfegh Nasir Mohajel Zabihollah Shoja |
| author_facet | Arash Arashkia Behrooz Nejati Mahsa Farsi Somayeh Jalilvand Alireza Nateghian Aliakbar Rahbarimanesh Fereshteh Moshfegh Nasir Mohajel Zabihollah Shoja |
| author_sort | Arash Arashkia |
| collection | DOAJ |
| description | Acute gastroenteritis is one of the most important causes of death in children in developing countries which cause by different enteropathogens, including bacteria, viruses, and parasites. Among these, most of the acute gastroenteritis in children are caused by viral infections mainly by rotavirus and norovirus. This study aimed to study the epidemiological and clinical status of acute gastroenteritis resulting from rotavirus and norovirus in children between June 2015 and June 2016 in Iran. A total of 211 stool specimens were collected from Ali Asghar Children's Hospital and Bahrami Children's Hospital in Tehran, from June 2015 to June 2016. The samples were screened by commercial enzyme immunoassay (EIA) Ridascreen kit and real time RT-PCR to detect rotavirus and norovirus genogroups I and II, respectively. The information on demographic and clinical manifestations was collected, and data analyzed using IBM SPSS statistics version 22. Overall, the detection rate of rotavirus was 25.6 %, and for norovirus infection, it was 17.5%. All norovirus positive specimens belonged to genogroup II. Higher rates of rotavirus infections were observed in children from 7 to 24 months, and higher rates of norovirus infections were detected in children from 1 to 12 months. Clinical symptoms were not different between rotavirus and norovirus case-patients. The present study not only highlights the importance of rotavirus and norovirus infections in Iran but also verifies the relevance of norovirus as the cause of severe gastroenteritis in children. |
| first_indexed | 2024-12-10T17:10:20Z |
| format | Article |
| id | doaj.art-1586c1550e084aa4adf7b8bc7024f3a5 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-12-10T17:10:20Z |
| publishDate | 2020-05-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-1586c1550e084aa4adf7b8bc7024f3a52022-12-22T01:40:20ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942020-05-01571110.18502/acta.v57i11.32807721Epidemiology and Clinical Characteristics of Rotavirus and Norovirus Infections in Hospitalized Children Less Than 5 Yaers of Age With Acute Gastroenteritis in Tehran, IranArash Arashkia0Behrooz Nejati1Mahsa Farsi2Somayeh Jalilvand3Alireza Nateghian4Aliakbar Rahbarimanesh5Fereshteh Moshfegh6Nasir Mohajel7Zabihollah Shoja8Department of Virology, Pasteur Institute of Iran, Tehran, Iran.Department of Virology, Pasteur Institute of Iran, Tehran, Iran . AND Department of Biology, Faculty of Basic Sciences, University of Mazandaran, Babolsar, Mazandaran, Iran.Department of Virology, Pasteur Institute of Iran, Tehran, Iran. AND Department of Biology, Faculty of Basic Sciences, University of Mazandaran, Babolsar, Mazandaran, Iran.Departmen of Virologyt, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.4Ali-Asghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran.Department of Pediatric Infectious Diseases, Bahrami Children's Hospital, Tehran University of Medical Sciences, Tehran, Iran.Ali-Asghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran.Department of Virology, Pasteur Institute of Iran, Tehran, Iran.Department of Virology, Pasteur Institute of Iran, Tehran, Iran.Acute gastroenteritis is one of the most important causes of death in children in developing countries which cause by different enteropathogens, including bacteria, viruses, and parasites. Among these, most of the acute gastroenteritis in children are caused by viral infections mainly by rotavirus and norovirus. This study aimed to study the epidemiological and clinical status of acute gastroenteritis resulting from rotavirus and norovirus in children between June 2015 and June 2016 in Iran. A total of 211 stool specimens were collected from Ali Asghar Children's Hospital and Bahrami Children's Hospital in Tehran, from June 2015 to June 2016. The samples were screened by commercial enzyme immunoassay (EIA) Ridascreen kit and real time RT-PCR to detect rotavirus and norovirus genogroups I and II, respectively. The information on demographic and clinical manifestations was collected, and data analyzed using IBM SPSS statistics version 22. Overall, the detection rate of rotavirus was 25.6 %, and for norovirus infection, it was 17.5%. All norovirus positive specimens belonged to genogroup II. Higher rates of rotavirus infections were observed in children from 7 to 24 months, and higher rates of norovirus infections were detected in children from 1 to 12 months. Clinical symptoms were not different between rotavirus and norovirus case-patients. The present study not only highlights the importance of rotavirus and norovirus infections in Iran but also verifies the relevance of norovirus as the cause of severe gastroenteritis in children.https://acta.tums.ac.ir/index.php/acta/article/view/7721RotavirusNorovirusAcute gastroenteritisClinical characteristics |
| spellingShingle | Arash Arashkia Behrooz Nejati Mahsa Farsi Somayeh Jalilvand Alireza Nateghian Aliakbar Rahbarimanesh Fereshteh Moshfegh Nasir Mohajel Zabihollah Shoja Epidemiology and Clinical Characteristics of Rotavirus and Norovirus Infections in Hospitalized Children Less Than 5 Yaers of Age With Acute Gastroenteritis in Tehran, Iran Acta Medica Iranica Rotavirus Norovirus Acute gastroenteritis Clinical characteristics |
| title | Epidemiology and Clinical Characteristics of Rotavirus and Norovirus Infections in Hospitalized Children Less Than 5 Yaers of Age With Acute Gastroenteritis in Tehran, Iran |
| title_full | Epidemiology and Clinical Characteristics of Rotavirus and Norovirus Infections in Hospitalized Children Less Than 5 Yaers of Age With Acute Gastroenteritis in Tehran, Iran |
| title_fullStr | Epidemiology and Clinical Characteristics of Rotavirus and Norovirus Infections in Hospitalized Children Less Than 5 Yaers of Age With Acute Gastroenteritis in Tehran, Iran |
| title_full_unstemmed | Epidemiology and Clinical Characteristics of Rotavirus and Norovirus Infections in Hospitalized Children Less Than 5 Yaers of Age With Acute Gastroenteritis in Tehran, Iran |
| title_short | Epidemiology and Clinical Characteristics of Rotavirus and Norovirus Infections in Hospitalized Children Less Than 5 Yaers of Age With Acute Gastroenteritis in Tehran, Iran |
| title_sort | epidemiology and clinical characteristics of rotavirus and norovirus infections in hospitalized children less than 5 yaers of age with acute gastroenteritis in tehran iran |
| topic | Rotavirus Norovirus Acute gastroenteritis Clinical characteristics |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/7721 |
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