Discordant Genome Assemblies Drastically Alter the Interpretation of Single-Cell RNA Sequencing Data Which Can Be Mitigated by a Novel Integration Method

Discordant Genome Assemblies Drastically Alter the Interpretation of Single-Cell RNA Sequencing Data Which Can Be Mitigated by a Novel Integration Method

Advances in sequencing and assembly technology have led to the creation of genome assemblies for a wide variety of non-model organisms. The rapid production and proliferation of updated, novel assembly versions can create vexing problems for researchers when multiple-genome assembly versions are ava...

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Bibliographic Details
Main Authors: Helen G. Potts, Madeleine E. Lemieux, Edward S. Rice, Wesley Warren, Robin P. Choudhury, Mathilda T. M. Mommersteeg
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
genome assembly
<i>Astyanax mexicanus</i>
integration
seurat
read alignment
non-model organisms
Online Access:https://www.mdpi.com/2073-4409/11/4/608

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