Results and possible prospects of genetic technology in ophthalmology (literature review). Part 2.

The emergence of fundamentally novel technological solutions in the field of gene therapy today, the formation of the priority and the development of genetic technologies create serious prerequisites for the beginning of a new Fusion era in ophthalmology in the near future. This review, in its secon...

Full description

Bibliographic Details
Main Authors: N. A. Gavrilova, O. Ie. Tishchenko, A. V. Zinov’eva
Format: Article
Language:English
Published: Ukrainian Society of Ophthalmologists 2021-04-01
Series:Journal of Ophthalmology
Subjects:
Online Access:https://www.ozhurnal.com/en/archive/2021/2/7-fulltext
_version_ 1797655920678797312
author N. A. Gavrilova
O. Ie. Tishchenko
A. V. Zinov’eva
author_facet N. A. Gavrilova
O. Ie. Tishchenko
A. V. Zinov’eva
author_sort N. A. Gavrilova
collection DOAJ
description The emergence of fundamentally novel technological solutions in the field of gene therapy today, the formation of the priority and the development of genetic technologies create serious prerequisites for the beginning of a new Fusion era in ophthalmology in the near future. This review, in its second part, presents the results of fundamental and clinical studies on the use of genetic therapeutic strategies – gene replacement, gene suppression, genomic editing using CRISPR / Cas9 technology which have been used in ophthalmology over the past several years.
first_indexed 2024-03-11T17:21:14Z
format Article
id doaj.art-158a9a4098714d688a8526f3db2f735a
institution Directory Open Access Journal
issn 2412-8740
language English
last_indexed 2024-03-11T17:21:14Z
publishDate 2021-04-01
publisher Ukrainian Society of Ophthalmologists
record_format Article
series Journal of Ophthalmology
spelling doaj.art-158a9a4098714d688a8526f3db2f735a2023-10-19T11:02:29ZengUkrainian Society of OphthalmologistsJournal of Ophthalmology2412-87402021-04-012404510.31288/oftalmolzh202124045Results and possible prospects of genetic technology in ophthalmology (literature review). Part 2.N. A. Gavrilova0O. Ie. Tishchenko1A. V. Zinov’eva2A.I. Evdokimov Moscow State University of Medicine and DentistryA.I. Evdokimov Moscow State University of Medicine and DentistryA.I. Evdokimov Moscow State University of Medicine and DentistryThe emergence of fundamentally novel technological solutions in the field of gene therapy today, the formation of the priority and the development of genetic technologies create serious prerequisites for the beginning of a new Fusion era in ophthalmology in the near future. This review, in its second part, presents the results of fundamental and clinical studies on the use of genetic therapeutic strategies – gene replacement, gene suppression, genomic editing using CRISPR / Cas9 technology which have been used in ophthalmology over the past several years.https://www.ozhurnal.com/en/archive/2021/2/7-fulltextsmall interfering rnasantisense nucleotidescrisprgene therapyretina
spellingShingle N. A. Gavrilova
O. Ie. Tishchenko
A. V. Zinov’eva
Results and possible prospects of genetic technology in ophthalmology (literature review). Part 2.
Journal of Ophthalmology
small interfering rnas
antisense nucleotides
crispr
gene therapy
retina
title Results and possible prospects of genetic technology in ophthalmology (literature review). Part 2.
title_full Results and possible prospects of genetic technology in ophthalmology (literature review). Part 2.
title_fullStr Results and possible prospects of genetic technology in ophthalmology (literature review). Part 2.
title_full_unstemmed Results and possible prospects of genetic technology in ophthalmology (literature review). Part 2.
title_short Results and possible prospects of genetic technology in ophthalmology (literature review). Part 2.
title_sort results and possible prospects of genetic technology in ophthalmology literature review part 2
topic small interfering rnas
antisense nucleotides
crispr
gene therapy
retina
url https://www.ozhurnal.com/en/archive/2021/2/7-fulltext
work_keys_str_mv AT nagavrilova resultsandpossibleprospectsofgenetictechnologyinophthalmologyliteraturereviewpart2
AT oietishchenko resultsandpossibleprospectsofgenetictechnologyinophthalmologyliteraturereviewpart2
AT avzinoveva resultsandpossibleprospectsofgenetictechnologyinophthalmologyliteraturereviewpart2