Valproic Acid Downregulates Cytokine Expression in Human Macrophages Infected with Dengue Virus

Valproic Acid Downregulates Cytokine Expression in Human Macrophages Infected with Dengue Virus

Natural infection with dengue virus (DENV) induces an increase in the production of cytokines that play an important role in disease pathogenesis. Despite numerous scientific studies, there are still no commercially available disease-specific therapeutics. Previous evidence shows that inhibiting his...

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Bibliographic Details
Main Authors: Félix G. Delgado, Paola Cárdenas, Jaime E. Castellanos
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Diseases
Subjects:
dengue virus
macrophage
cytokines
HDAC inhibitors
valproic acid
Online Access:http://www.mdpi.com/2079-9721/6/3/59

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