A photodynamic-mediated glutamine metabolic intervention nanodrug for triple negative breast cancer therapy

A photodynamic-mediated glutamine metabolic intervention nanodrug for triple negative breast cancer therapy

“Glutamine addiction” is a unique feature of triple negative breast cancer (TNBC), which has a higher demand for glutamine and is more susceptible to glutamine depletion. Glutamine can be hydrolyzed to glutamate by glutaminase (GLS) for synthesis of glutathione (GSH), which is an important downstrea...

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Bibliographic Details
Main Authors:	Cancan Yu, Ningning Wang, Xiangwu Chen, Yue Jiang, Yuxia Luan, Wen Qin, Wenxiu He
Format:	Article
Language:	English
Published:	Elsevier 2023-04-01
Series:	Materials Today Bio
Subjects:	Photodynamic therapy Glutamine metabolic intervention BPTES Ce6 Triple negative breast cancer
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590006423000376

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