Diagnostic capabilities of monitoring of redox potential in blood plasma of lung transplant patients
Introduction. Monitoring of redox potential (platinum electrode open circuit potential) in biological media (serum, blood plasma) is one of the promising methods for diagnosing and predicting the development of complications in patients in the early post-transplantation period. The study of the diag...
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| Format: | Article |
| Language: | English |
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N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2019-06-01
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| Series: | Трансплантология (Москва) |
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| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/429 |
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| author | A. K. Evseev E. I. Pervakova I. V. Goroncharovskaya E. A. Tarabrin M. Sh. Khubutiya M. M. Goldin |
| author_facet | A. K. Evseev E. I. Pervakova I. V. Goroncharovskaya E. A. Tarabrin M. Sh. Khubutiya M. M. Goldin |
| author_sort | A. K. Evseev |
| collection | DOAJ |
| description | Introduction. Monitoring of redox potential (platinum electrode open circuit potential) in biological media (serum, blood plasma) is one of the promising methods for diagnosing and predicting the development of complications in patients in the early post-transplantation period. The study of the diagnostic capabilities of this technique in patients after lung transplantation is highly relevant.The objective was to assess the diagnostic and prognostic capabilities of monitoring platinum electrode open circuit potential in blood plasma of lung transplant patients.Material and methods. The data obtained at monitoring of platinum electrode open circuit potential in blood plasma and clinical laboratory test results of 14 patients after double lung transplantation surgery were analyzed. The platinum electrode open circuit potential value in the blood plasma was measured by the potentiometric method.Results. The study demonstrated the differences in the dynamics and values of platinum electrode open circuit potential in the blood plasma between the lung transplant patients with a favorable outcome and those with a fatal outcome. Wave-like segments on the relationship curves of the platinum electrode open circuit potential in blood plasma to time coincided with inflammatory markers (C-reactive protein, stab neutrophils, erythrocyte sedimentation rate) activation. Statistically significant correlations between platinum electrode open circuit potential values in blood plasma and clinical laboratory test results were revealed.Conclusion. The informative value and diagnostic capabilities of the technique of the platinum electrode open circuit potential measurement in blood plasma of lung transplant patients have prospects of using its results as a criterion for assessing the patient’s condition and improving the quality of therapy. |
| first_indexed | 2024-03-12T04:57:24Z |
| format | Article |
| id | doaj.art-1591fabc04a14eec9d607672b575e80b |
| institution | Directory Open Access Journal |
| issn | 2074-0506 2542-0909 |
| language | English |
| last_indexed | 2024-03-12T04:57:24Z |
| publishDate | 2019-06-01 |
| publisher | N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department |
| record_format | Article |
| series | Трансплантология (Москва) |
| spelling | doaj.art-1591fabc04a14eec9d607672b575e80b2023-09-03T09:14:39ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092019-06-0111212814010.23873/2074-0506-2019-11-2-128-140407Diagnostic capabilities of monitoring of redox potential in blood plasma of lung transplant patientsA. K. Evseev0E. I. Pervakova1I. V. Goroncharovskaya2E. A. Tarabrin3M. Sh. Khubutiya4M. M. Goldin5ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»Колледж Глен Окс КоммьюнитиIntroduction. Monitoring of redox potential (platinum electrode open circuit potential) in biological media (serum, blood plasma) is one of the promising methods for diagnosing and predicting the development of complications in patients in the early post-transplantation period. The study of the diagnostic capabilities of this technique in patients after lung transplantation is highly relevant.The objective was to assess the diagnostic and prognostic capabilities of monitoring platinum electrode open circuit potential in blood plasma of lung transplant patients.Material and methods. The data obtained at monitoring of platinum electrode open circuit potential in blood plasma and clinical laboratory test results of 14 patients after double lung transplantation surgery were analyzed. The platinum electrode open circuit potential value in the blood plasma was measured by the potentiometric method.Results. The study demonstrated the differences in the dynamics and values of platinum electrode open circuit potential in the blood plasma between the lung transplant patients with a favorable outcome and those with a fatal outcome. Wave-like segments on the relationship curves of the platinum electrode open circuit potential in blood plasma to time coincided with inflammatory markers (C-reactive protein, stab neutrophils, erythrocyte sedimentation rate) activation. Statistically significant correlations between platinum electrode open circuit potential values in blood plasma and clinical laboratory test results were revealed.Conclusion. The informative value and diagnostic capabilities of the technique of the platinum electrode open circuit potential measurement in blood plasma of lung transplant patients have prospects of using its results as a criterion for assessing the patient’s condition and improving the quality of therapy.https://www.jtransplantologiya.ru/jour/article/view/429трансплантация легкихпотенциал при разомкнутой цепиплатиновый электродплазма кровивоспалительный процессосложнение |
| spellingShingle | A. K. Evseev E. I. Pervakova I. V. Goroncharovskaya E. A. Tarabrin M. Sh. Khubutiya M. M. Goldin Diagnostic capabilities of monitoring of redox potential in blood plasma of lung transplant patients Трансплантология (Москва) трансплантация легких потенциал при разомкнутой цепи платиновый электрод плазма крови воспалительный процесс осложнение |
| title | Diagnostic capabilities of monitoring of redox potential in blood plasma of lung transplant patients |
| title_full | Diagnostic capabilities of monitoring of redox potential in blood plasma of lung transplant patients |
| title_fullStr | Diagnostic capabilities of monitoring of redox potential in blood plasma of lung transplant patients |
| title_full_unstemmed | Diagnostic capabilities of monitoring of redox potential in blood plasma of lung transplant patients |
| title_short | Diagnostic capabilities of monitoring of redox potential in blood plasma of lung transplant patients |
| title_sort | diagnostic capabilities of monitoring of redox potential in blood plasma of lung transplant patients |
| topic | трансплантация легких потенциал при разомкнутой цепи платиновый электрод плазма крови воспалительный процесс осложнение |
| url | https://www.jtransplantologiya.ru/jour/article/view/429 |
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