The Frequency and Effect of Granulocytic Myeloid-Derived Suppressor Cells on Mycobacterial Survival in Patients With Tuberculosis: A Preliminary Report

The Frequency and Effect of Granulocytic Myeloid-Derived Suppressor Cells on Mycobacterial Survival in Patients With Tuberculosis: A Preliminary Report

IntroductionProtective host responses in those exposed to or infected with tuberculosis (TB) is thought to require a delicate balance between pro-inflammatory and regulatory immune responses. Myeloid-derived suppressor cells (MDSCs), regulatory cells that dampen T-cell function, have been described...

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Bibliographic Details
Main Authors: Malika Davids, Anil Pooran, Liezel Smith, Michele Tomasicchio, Keertan Dheda
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
myeloid derived suppressor cells
MDSC
tuberculosis
immunology
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.676679/full

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