Epigenetically upregulated NSUN2 confers ferroptosis resistance in endometrial cancer via m5C modification of SLC7A11 mRNA

Epigenetically upregulated NSUN2 confers ferroptosis resistance in endometrial cancer via m5C modification of SLC7A11 mRNA

Endometrial cancer (EC) is a prevalent gynecological malignancy worldwide, and 5-methylcytosine (m5C) modification of mRNA is a crucial epigenetic modification associated with the development and occurrence of several cancers. However, the precise function of m5C modification in EC remains elusive....

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Bibliographic Details
Main Authors: Shuai-Jun Chen, Jun Zhang, Ting Zhou, Shan-Shan Rao, Qian Li, Ling-Yan Xiao, Si-Tian Wei, Hong-Feng Zhang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Redox Biology
Subjects:
NSUN2
SLC7A11
m5C
Endometrial cancer
Ferroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723003762

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