Fulminant Leptospirosis: an autopsy case
Leptospirosis is an acute febrile illness affecting humans and/or animals, with a high global incidence mainly in the tropical developing countries. Outbreaks are frequently related to rainy season, floods and the presence of reservoirs animals more commonly rodents and dogs. The disease occurs in t...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of São Paulo
2011-06-01
|
| Series: | Autopsy and Case Reports |
| Subjects: | |
| Online Access: | http://www.revistas.usp.br/autopsy/article/view/36416 |
| _version_ | 1831748385929953280 |
|---|---|
| author | Fernando Peixoto Ferraz de Campos Angélica Braz Simões |
| author_facet | Fernando Peixoto Ferraz de Campos Angélica Braz Simões |
| author_sort | Fernando Peixoto Ferraz de Campos |
| collection | DOAJ |
| description | Leptospirosis is an acute febrile illness affecting humans and/or animals, with a high global incidence mainly in the tropical developing countries. Outbreaks are frequently related to rainy season, floods and the presence of reservoirs animals more commonly rodents and dogs. The disease occurs in the rural and urban areas linked to some occupational and recreational activities. The younger population is at higher risk of infection. Approximately 5% - 15% of the patients develop the severe
manifestations of the disease known as Weill’s disease that can be associated with leptospirosis pulmonary hemorrhage syndrome. We present an autopsy case of an octogenarian patient, resident of the urban area of the city of São Paulo, admitted to the Hospital Universitário da Universidade de São Paulo, who presented a fulminant outcome. The autopsy revealed pulmonary involvement characterized by diffuse alveolar hemorrhage and interstitial mononuclear infiltration. The liver histology presented disorganization of the liver cell plates, congested sinusoids and Kupfer cells hyperplasia. Acute tubular necrosis and interstitial nephritis was the hallmark of kidneys involvment. |
| first_indexed | 2024-12-21T21:50:48Z |
| format | Article |
| id | doaj.art-159a153419a14619bd698e0e19a7faec |
| institution | Directory Open Access Journal |
| issn | 2236-1960 |
| language | English |
| last_indexed | 2024-12-21T21:50:48Z |
| publishDate | 2011-06-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Autopsy and Case Reports |
| spelling | doaj.art-159a153419a14619bd698e0e19a7faec2022-12-21T18:49:06ZengUniversity of São PauloAutopsy and Case Reports2236-19602011-06-011210.4322/acr.2016.00436324Fulminant Leptospirosis: an autopsy caseFernando Peixoto Ferraz de CamposAngélica Braz SimõesLeptospirosis is an acute febrile illness affecting humans and/or animals, with a high global incidence mainly in the tropical developing countries. Outbreaks are frequently related to rainy season, floods and the presence of reservoirs animals more commonly rodents and dogs. The disease occurs in the rural and urban areas linked to some occupational and recreational activities. The younger population is at higher risk of infection. Approximately 5% - 15% of the patients develop the severe manifestations of the disease known as Weill’s disease that can be associated with leptospirosis pulmonary hemorrhage syndrome. We present an autopsy case of an octogenarian patient, resident of the urban area of the city of São Paulo, admitted to the Hospital Universitário da Universidade de São Paulo, who presented a fulminant outcome. The autopsy revealed pulmonary involvement characterized by diffuse alveolar hemorrhage and interstitial mononuclear infiltration. The liver histology presented disorganization of the liver cell plates, congested sinusoids and Kupfer cells hyperplasia. Acute tubular necrosis and interstitial nephritis was the hallmark of kidneys involvment.http://www.revistas.usp.br/autopsy/article/view/36416LeptospirosisWeil’s diseaseRespiratory InsufficiencyAcute renal. |
| spellingShingle | Fernando Peixoto Ferraz de Campos Angélica Braz Simões Fulminant Leptospirosis: an autopsy case Autopsy and Case Reports Leptospirosis Weil’s disease Respiratory Insufficiency Acute renal. |
| title | Fulminant Leptospirosis: an autopsy case |
| title_full | Fulminant Leptospirosis: an autopsy case |
| title_fullStr | Fulminant Leptospirosis: an autopsy case |
| title_full_unstemmed | Fulminant Leptospirosis: an autopsy case |
| title_short | Fulminant Leptospirosis: an autopsy case |
| title_sort | fulminant leptospirosis an autopsy case |
| topic | Leptospirosis Weil’s disease Respiratory Insufficiency Acute renal. |
| url | http://www.revistas.usp.br/autopsy/article/view/36416 |
| work_keys_str_mv | AT fernandopeixotoferrazdecampos fulminantleptospirosisanautopsycase AT angelicabrazsimoes fulminantleptospirosisanautopsycase |