Graphene-Based Ion-Selective Field-Effect Transistor for Sodium Sensing
Field-effect transistors have attracted significant attention in chemical sensing and clinical diagnosis, due to their high sensitivity and label-free operation. Through a scalable photolithographic process in this study, we fabricated graphene-based ion-sensitive field-effect transistor (ISFET) arr...
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| Format: | Article |
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MDPI AG
2022-07-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/15/2620 |
| _version_ | 1797441128767684608 |
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| author | Ting Huang Kan Kan Yeung Jingwei Li Honglin Sun Md Masruck Alam Zhaoli Gao |
| author_facet | Ting Huang Kan Kan Yeung Jingwei Li Honglin Sun Md Masruck Alam Zhaoli Gao |
| author_sort | Ting Huang |
| collection | DOAJ |
| description | Field-effect transistors have attracted significant attention in chemical sensing and clinical diagnosis, due to their high sensitivity and label-free operation. Through a scalable photolithographic process in this study, we fabricated graphene-based ion-sensitive field-effect transistor (ISFET) arrays that can continuously monitor sodium ions in real-time. As the sodium ion concentration increased, the current–gate voltage characteristic curves shifted towards the negative direction, showing that sodium ions were captured and could be detected over a wide concentration range, from 10<sup>−8</sup> to 10<sup>−1</sup> M, with a sensitivity of 152.4 mV/dec. Time-dependent measurements and interfering experiments were conducted to validate the real-time measurements and the highly specific detection capability of our sensor. Our graphene ISFETs (G-ISFET) not only showed a fast response, but also exhibited remarkable selectivity against interference ions, including Ca<sup>2+</sup>, K<sup>+</sup>, Mg<sup>2+</sup> and NH<sub>4</sub><sup>+</sup>. The scalability, high sensitivity and selectivity synergistically make our G-ISFET a promising platform for sodium sensing in health monitoring. |
| first_indexed | 2024-03-09T12:19:32Z |
| format | Article |
| id | doaj.art-159a895b6b164fa1a757ea7d299d511a |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T12:19:32Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-159a895b6b164fa1a757ea7d299d511a2023-11-30T22:42:38ZengMDPI AGNanomaterials2079-49912022-07-011215262010.3390/nano12152620Graphene-Based Ion-Selective Field-Effect Transistor for Sodium SensingTing Huang0Kan Kan Yeung1Jingwei Li2Honglin Sun3Md Masruck Alam4Zhaoli Gao5Biomedical Engineering Department, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, ChinaBiomedical Engineering Department, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, ChinaBiomedical Engineering Department, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, ChinaBiomedical Engineering Department, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, ChinaBiomedical Engineering Department, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, ChinaBiomedical Engineering Department, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, ChinaField-effect transistors have attracted significant attention in chemical sensing and clinical diagnosis, due to their high sensitivity and label-free operation. Through a scalable photolithographic process in this study, we fabricated graphene-based ion-sensitive field-effect transistor (ISFET) arrays that can continuously monitor sodium ions in real-time. As the sodium ion concentration increased, the current–gate voltage characteristic curves shifted towards the negative direction, showing that sodium ions were captured and could be detected over a wide concentration range, from 10<sup>−8</sup> to 10<sup>−1</sup> M, with a sensitivity of 152.4 mV/dec. Time-dependent measurements and interfering experiments were conducted to validate the real-time measurements and the highly specific detection capability of our sensor. Our graphene ISFETs (G-ISFET) not only showed a fast response, but also exhibited remarkable selectivity against interference ions, including Ca<sup>2+</sup>, K<sup>+</sup>, Mg<sup>2+</sup> and NH<sub>4</sub><sup>+</sup>. The scalability, high sensitivity and selectivity synergistically make our G-ISFET a promising platform for sodium sensing in health monitoring.https://www.mdpi.com/2079-4991/12/15/2620ion-selective field-effect transistorgraphenesodium ionsreal-time monitoring |
| spellingShingle | Ting Huang Kan Kan Yeung Jingwei Li Honglin Sun Md Masruck Alam Zhaoli Gao Graphene-Based Ion-Selective Field-Effect Transistor for Sodium Sensing Nanomaterials ion-selective field-effect transistor graphene sodium ions real-time monitoring |
| title | Graphene-Based Ion-Selective Field-Effect Transistor for Sodium Sensing |
| title_full | Graphene-Based Ion-Selective Field-Effect Transistor for Sodium Sensing |
| title_fullStr | Graphene-Based Ion-Selective Field-Effect Transistor for Sodium Sensing |
| title_full_unstemmed | Graphene-Based Ion-Selective Field-Effect Transistor for Sodium Sensing |
| title_short | Graphene-Based Ion-Selective Field-Effect Transistor for Sodium Sensing |
| title_sort | graphene based ion selective field effect transistor for sodium sensing |
| topic | ion-selective field-effect transistor graphene sodium ions real-time monitoring |
| url | https://www.mdpi.com/2079-4991/12/15/2620 |
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