MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS
Morphological and physico-chemical properties of erythrocytes encapsulated by terpenoindol alkaloids (TIA) by nephelometry and osmotic resistance of erythrocytes in a medium with low concentrations of sodium chloride have been studied. Changes in the morphological and physico-chemical parameters of...
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Format: | Article |
Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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Series: | Разработка и регистрация лекарственных средств |
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Online Access: | https://www.pharmjournal.ru/jour/article/view/557 |
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author | O. V. Trineeva A. J. Halahakoon A. I. Slivkin E. E. Chupandina |
author_facet | O. V. Trineeva A. J. Halahakoon A. I. Slivkin E. E. Chupandina |
author_sort | O. V. Trineeva |
collection | DOAJ |
description | Morphological and physico-chemical properties of erythrocytes encapsulated by terpenoindol alkaloids (TIA) by nephelometry and osmotic resistance of erythrocytes in a medium with low concentrations of sodium chloride have been studied. Changes in the morphological and physico-chemical parameters of TIA-loaded erythrocyte carriers and freshly isolated erythrocytes have been studied. It was found that during the process of encapsulation of TIA by a modified hypotonic swelling method, the morphological and physicochemical parameters of erythrocytes change insignificantly in comparison with the control. |
first_indexed | 2024-04-10T01:39:51Z |
format | Article |
id | doaj.art-159f8da835dc4392a4af2717e980271c |
institution | Directory Open Access Journal |
issn | 2305-2066 2658-5049 |
language | Russian |
last_indexed | 2024-04-10T01:39:51Z |
publishDate | 2019-01-01 |
publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
record_format | Article |
series | Разработка и регистрация лекарственных средств |
spelling | doaj.art-159f8da835dc4392a4af2717e980271c2023-03-13T09:13:59ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0101146150557MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDSO. V. Trineeva0A. J. Halahakoon1A. I. Slivkin2E. E. Chupandina3ФГБОУ ВО «Воронежский государственный университет»ФГБОУ ВО «Воронежский государственный университет»ФГБОУ ВО «Воронежский государственный университет»ФГБОУ ВО «Воронежский государственный университет»Morphological and physico-chemical properties of erythrocytes encapsulated by terpenoindol alkaloids (TIA) by nephelometry and osmotic resistance of erythrocytes in a medium with low concentrations of sodium chloride have been studied. Changes in the morphological and physico-chemical parameters of TIA-loaded erythrocyte carriers and freshly isolated erythrocytes have been studied. It was found that during the process of encapsulation of TIA by a modified hypotonic swelling method, the morphological and physicochemical parameters of erythrocytes change insignificantly in comparison with the control.https://www.pharmjournal.ru/jour/article/view/557эритроцитарные носителитерпеноиндольные алкалоидынефелометриярефрактометрияадресные системы доставки лекарственных средств |
spellingShingle | O. V. Trineeva A. J. Halahakoon A. I. Slivkin E. E. Chupandina MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS Разработка и регистрация лекарственных средств эритроцитарные носители терпеноиндольные алкалоиды нефелометрия рефрактометрия адресные системы доставки лекарственных средств |
title | MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS |
title_full | MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS |
title_fullStr | MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS |
title_full_unstemmed | MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS |
title_short | MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS |
title_sort | morphological and physico chemical properties of erythrocyte carriers incapulated by terpineindolicalk aloids |
topic | эритроцитарные носители терпеноиндольные алкалоиды нефелометрия рефрактометрия адресные системы доставки лекарственных средств |
url | https://www.pharmjournal.ru/jour/article/view/557 |
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