MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS

Morphological and physico-chemical properties of erythrocytes encapsulated by terpenoindol alkaloids (TIA) by nephelometry and osmotic resistance of erythrocytes in a medium with low concentrations of sodium chloride have been studied. Changes in the morphological and physico-chemical parameters of...

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Main Authors: O. V. Trineeva, A. J. Halahakoon, A. I. Slivkin, E. E. Chupandina
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/557
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author O. V. Trineeva
A. J. Halahakoon
A. I. Slivkin
E. E. Chupandina
author_facet O. V. Trineeva
A. J. Halahakoon
A. I. Slivkin
E. E. Chupandina
author_sort O. V. Trineeva
collection DOAJ
description Morphological and physico-chemical properties of erythrocytes encapsulated by terpenoindol alkaloids (TIA) by nephelometry and osmotic resistance of erythrocytes in a medium with low concentrations of sodium chloride have been studied. Changes in the morphological and physico-chemical parameters of TIA-loaded erythrocyte carriers and freshly isolated erythrocytes have been studied. It was found that during the process of encapsulation of TIA by a modified hypotonic swelling method, the morphological and physicochemical parameters of erythrocytes change insignificantly in comparison with the control.
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last_indexed 2024-04-10T01:39:51Z
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spelling doaj.art-159f8da835dc4392a4af2717e980271c2023-03-13T09:13:59ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0101146150557MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDSO. V. Trineeva0A. J. Halahakoon1A. I. Slivkin2E. E. Chupandina3ФГБОУ ВО «Воронежский государственный университет»ФГБОУ ВО «Воронежский государственный университет»ФГБОУ ВО «Воронежский государственный университет»ФГБОУ ВО «Воронежский государственный университет»Morphological and physico-chemical properties of erythrocytes encapsulated by terpenoindol alkaloids (TIA) by nephelometry and osmotic resistance of erythrocytes in a medium with low concentrations of sodium chloride have been studied. Changes in the morphological and physico-chemical parameters of TIA-loaded erythrocyte carriers and freshly isolated erythrocytes have been studied. It was found that during the process of encapsulation of TIA by a modified hypotonic swelling method, the morphological and physicochemical parameters of erythrocytes change insignificantly in comparison with the control.https://www.pharmjournal.ru/jour/article/view/557эритроцитарные носителитерпеноиндольные алкалоидынефелометриярефрактометрияадресные системы доставки лекарственных средств
spellingShingle O. V. Trineeva
A. J. Halahakoon
A. I. Slivkin
E. E. Chupandina
MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS
Разработка и регистрация лекарственных средств
эритроцитарные носители
терпеноиндольные алкалоиды
нефелометрия
рефрактометрия
адресные системы доставки лекарственных средств
title MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS
title_full MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS
title_fullStr MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS
title_full_unstemmed MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS
title_short MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS
title_sort morphological and physico chemical properties of erythrocyte carriers incapulated by terpineindolicalk aloids
topic эритроцитарные носители
терпеноиндольные алкалоиды
нефелометрия
рефрактометрия
адресные системы доставки лекарственных средств
url https://www.pharmjournal.ru/jour/article/view/557
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