Identification of interferon-stimulated genes that attenuate Ebola virus infection

Identification of interferon-stimulated genes that attenuate Ebola virus infection

Here, Kuroda et al. screen a library of nearly 400 interferon-stimulated genes (ISGs) and identify several ISGs that inhibit Ebola virus entry, viral transcription/replication, or virion formation. The study provides insights into interactions between Ebola and the host cells.

Bibliographic Details
Main Authors: Makoto Kuroda, Peter J. Halfmann, Lindsay Hill-Batorski, Makoto Ozawa, Tiago J. S. Lopes, Gabriele Neumann, John W. Schoggins, Charles M. Rice, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Nature Portfolio 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16768-7
Description
Summary:Here, Kuroda et al. screen a library of nearly 400 interferon-stimulated genes (ISGs) and identify several ISGs that inhibit Ebola virus entry, viral transcription/replication, or virion formation. The study provides insights into interactions between Ebola and the host cells.
ISSN:2041-1723

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