Pulmonary Aerosol Delivery of Let‐7b microRNA Confers a Striking Inhibitory Effect on Lung Carcinogenesis through Targeting the Tumor Immune Microenvironment

Pulmonary Aerosol Delivery of Let‐7b microRNA Confers a Striking Inhibitory Effect on Lung Carcinogenesis through Targeting the Tumor Immune Microenvironment

Abstract MicroRNAs are potential candidates for lung cancer prevention and therapy. A major limitation is the lack of an efficient delivery system to directly deliver miRNA to cancer cells while limiting systemic exposure. The delivery of miRNA via inhalation is a potential strategy for lung cancer...

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Bibliographic Details
Main Authors: Qi Zhang, Jing Pan, Donghai Xiong, Yian Wang, Mark Steven Miller, Shizuko Sei, Robert H. Shoemaker, Alberto Izzotti, Ming You
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Advanced Science
Subjects:
immunity
let‐7b
lung cancer
miRNA
pulmonary aerosol delivery
single‐cell RNA sequencing
Online Access:https://doi.org/10.1002/advs.202100629

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