Variation in olfactory neuron repertoires is genetically controlled and environmentally modulated

Variation in olfactory neuron repertoires is genetically controlled and environmentally modulated

The mouse olfactory sensory neuron (OSN) repertoire is composed of 10 million cells and each expresses one olfactory receptor (OR) gene from a pool of over 1000. Thus, the nose is sub-stratified into more than a thousand OSN subtypes. Here, we employ and validate an RNA-sequencing-based method to qu...

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Bibliographic Details
Main Authors: Ximena Ibarra-Soria, Thiago S Nakahara, Jingtao Lilue, Yue Jiang, Casey Trimmer, Mateus AA Souza, Paulo HM Netto, Kentaro Ikegami, Nicolle R Murphy, Mairi Kusma, Andrea Kirton, Luis R Saraiva, Thomas M Keane, Hiroaki Matsunami, Joel Mainland, Fabio Papes, Darren W Logan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-04-01
Series:eLife
Subjects:
olfactory receptor
RNAseq
variation
genetic regulation
environmental regulation
Online Access:https://elifesciences.org/articles/21476

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