Structural, Mechanical, and Dielectric Properties of Polydimethylsiloxane and Silicone Elastomer for the Fabrication of Clinical-Grade Kidney Phantom

This study aimed to introduce an alternative, inexpensive, and straightforward polymer with specific mechanical and dielectric properties suitable for the fabrication of a clinical-grade kidney phantom. Two polymer-based phantom materials, polydimethylsiloxane (PDMS) and silicone elastomer (SE), wer...

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Main Authors: Kamal Izdihar, Hairil Rashmizal Abdul Razak, Nurzulaikha Supion, Muhammad Khalis Abdul Karim, Nurul Huda Osman, Mazlan Norkhairunnisa
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/11/3/1172
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author Kamal Izdihar
Hairil Rashmizal Abdul Razak
Nurzulaikha Supion
Muhammad Khalis Abdul Karim
Nurul Huda Osman
Mazlan Norkhairunnisa
author_facet Kamal Izdihar
Hairil Rashmizal Abdul Razak
Nurzulaikha Supion
Muhammad Khalis Abdul Karim
Nurul Huda Osman
Mazlan Norkhairunnisa
author_sort Kamal Izdihar
collection DOAJ
description This study aimed to introduce an alternative, inexpensive, and straightforward polymer with specific mechanical and dielectric properties suitable for the fabrication of a clinical-grade kidney phantom. Two polymer-based phantom materials, polydimethylsiloxane (PDMS) and silicone elastomer (SE), were investigated for their capability to meet the requirements. The concentration ratios of base to curing agent (B/C) were 9.5/1.5, 19/3, 10/1, 20/2, 10.5/0.5, and 21/1 for PDMS and 4.5/5.5, 10/12, 5/5, 11/11, 5.5/4.5, and 12/10 for SE. All samples were mixed, degassed, and poured into Petri dishes and small beakers. The polymer was cured under room temperature for 2 h and then demolded from the hard mold. The air bubbles produced were removed using a vacuum desiccator for 30 min. All samples underwent mechanical testing (tensile strength and elastic modulus), and their dielectric properties were measured using a dielectric probe kit equipped with 85071E materials measurement software. The radiation attenuation properties were also measured using PhyX-Zetra for PDMS phantoms with the chemical formula C<sub>2</sub>H<sub>6</sub>OSi. Small changes in base and cross-linker play an essential role in modifying the elastic modulus and tensile strength. The effective atomic number of PDMS showed a similar pattern with human kidney tissue at the intermediate energy level of 1.50 × 10<sup>−1</sup> to 1 MeV. Therefore, PDMS can potentially be used to mimic the human kidney in terms of tensile strength, flexibility, the acceptable real part of the complex dielectric constant <i>ε′r</i>, and conductivity, which allows it to be used as a stable kidney phantom for medical imaging purposes.
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spelling doaj.art-15abf7ff20fe4c33a653739412caf0702023-12-03T14:55:00ZengMDPI AGApplied Sciences2076-34172021-01-01113117210.3390/app11031172Structural, Mechanical, and Dielectric Properties of Polydimethylsiloxane and Silicone Elastomer for the Fabrication of Clinical-Grade Kidney PhantomKamal Izdihar0Hairil Rashmizal Abdul Razak1Nurzulaikha Supion2Muhammad Khalis Abdul Karim3Nurul Huda Osman4Mazlan Norkhairunnisa5Department of Radiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Seri Kembangan 43400, Selangor, MalaysiaDepartment of Radiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Seri Kembangan 43400, Selangor, MalaysiaDepartment of Medical Imaging, School of Health Sciences, KPJ Healthcare University College, Nilai 71800, N. Sembilan, MalaysiaDepartment of Physics, Faculty of Science, Universiti Putra Malaysia, Seri Kembangan 43400, Selangor, MalaysiaDepartment of Physics, Faculty of Science, Universiti Putra Malaysia, Seri Kembangan 43400, Selangor, MalaysiaDepartment of Aerospace Engineering, Faculty of Engineering, Universiti Putra Malaysia, Seri Kembangan 43400, Selangor, MalaysiaThis study aimed to introduce an alternative, inexpensive, and straightforward polymer with specific mechanical and dielectric properties suitable for the fabrication of a clinical-grade kidney phantom. Two polymer-based phantom materials, polydimethylsiloxane (PDMS) and silicone elastomer (SE), were investigated for their capability to meet the requirements. The concentration ratios of base to curing agent (B/C) were 9.5/1.5, 19/3, 10/1, 20/2, 10.5/0.5, and 21/1 for PDMS and 4.5/5.5, 10/12, 5/5, 11/11, 5.5/4.5, and 12/10 for SE. All samples were mixed, degassed, and poured into Petri dishes and small beakers. The polymer was cured under room temperature for 2 h and then demolded from the hard mold. The air bubbles produced were removed using a vacuum desiccator for 30 min. All samples underwent mechanical testing (tensile strength and elastic modulus), and their dielectric properties were measured using a dielectric probe kit equipped with 85071E materials measurement software. The radiation attenuation properties were also measured using PhyX-Zetra for PDMS phantoms with the chemical formula C<sub>2</sub>H<sub>6</sub>OSi. Small changes in base and cross-linker play an essential role in modifying the elastic modulus and tensile strength. The effective atomic number of PDMS showed a similar pattern with human kidney tissue at the intermediate energy level of 1.50 × 10<sup>−1</sup> to 1 MeV. Therefore, PDMS can potentially be used to mimic the human kidney in terms of tensile strength, flexibility, the acceptable real part of the complex dielectric constant <i>ε′r</i>, and conductivity, which allows it to be used as a stable kidney phantom for medical imaging purposes.https://www.mdpi.com/2076-3417/11/3/1172mechanicaldielectriceffective atomic numberPDMSsilicone elastomerkidney phantom
spellingShingle Kamal Izdihar
Hairil Rashmizal Abdul Razak
Nurzulaikha Supion
Muhammad Khalis Abdul Karim
Nurul Huda Osman
Mazlan Norkhairunnisa
Structural, Mechanical, and Dielectric Properties of Polydimethylsiloxane and Silicone Elastomer for the Fabrication of Clinical-Grade Kidney Phantom
Applied Sciences
mechanical
dielectric
effective atomic number
PDMS
silicone elastomer
kidney phantom
title Structural, Mechanical, and Dielectric Properties of Polydimethylsiloxane and Silicone Elastomer for the Fabrication of Clinical-Grade Kidney Phantom
title_full Structural, Mechanical, and Dielectric Properties of Polydimethylsiloxane and Silicone Elastomer for the Fabrication of Clinical-Grade Kidney Phantom
title_fullStr Structural, Mechanical, and Dielectric Properties of Polydimethylsiloxane and Silicone Elastomer for the Fabrication of Clinical-Grade Kidney Phantom
title_full_unstemmed Structural, Mechanical, and Dielectric Properties of Polydimethylsiloxane and Silicone Elastomer for the Fabrication of Clinical-Grade Kidney Phantom
title_short Structural, Mechanical, and Dielectric Properties of Polydimethylsiloxane and Silicone Elastomer for the Fabrication of Clinical-Grade Kidney Phantom
title_sort structural mechanical and dielectric properties of polydimethylsiloxane and silicone elastomer for the fabrication of clinical grade kidney phantom
topic mechanical
dielectric
effective atomic number
PDMS
silicone elastomer
kidney phantom
url https://www.mdpi.com/2076-3417/11/3/1172
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