How microscopic epistasis and clonal interference shape the fitness trajectory in a spin glass model of microbial long-term evolution
The adaptive dynamics of evolving microbial populations takes place on a complex fitness landscape generated by epistatic interactions. The population generically consists of multiple competing strains, a phenomenon known as clonal interference. Microscopic epistasis and clonal interference are cent...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2024-02-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/87895 |