Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model

Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model

<p>Abstract</p> <p>Background</p> <p>Alpha-1 antitrypsin (AAT) is a multi-functional protein that has anti-inflammatory and tissue protective properties. We previously reported that human AAT (hAAT) gene therapy prevented autoimmune diabetes in non-obese diabetic (NOD)...

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Bibliographic Details
Main Authors: Atkinson Mark A, Satoh Minoru, Wasserfall Clive H, Choi Young-Kook, Grimstein Christian, Brantly Mark L, Campbell-Thompson Martha, Song Sihong
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/21

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