The Role of Non-Steroidal Anti-Inflammatory Drugs in Renal Colic

NSAIDs provide optimal analgesia in renal colic due to the reduction in glomerular filtration and renal pelvic pressure, ureteric peristalsis and ureteric oedema. Prevention of glomerular afferent arteriolar vasodilatation renders these patients at risk of renal impairment. NSAIDs have the additiona...

Full description

Bibliographic Details
Main Authors: Elizabeth Waine, Kim Davenport
Format: Article
Language:English
Published: MDPI AG 2010-04-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/3/5/1304/
Description
Summary:NSAIDs provide optimal analgesia in renal colic due to the reduction in glomerular filtration and renal pelvic pressure, ureteric peristalsis and ureteric oedema. Prevention of glomerular afferent arteriolar vasodilatation renders these patients at risk of renal impairment. NSAIDs have the additional benefit of reducing the number of new colic episodes and preventing subsequent readmission to hospital. Despite recent work promoting the use of pharmacological agents to improve stone passage rates, NSAIDs do not appear to reduce the time to stone passage or increase the likelihood of stone passage in renal colic.
ISSN:1424-8247